Reproducible Dispensing of Liquids in the Nanolitre Range

Grünwald, Stefan

doi:10.1007/s35784-018-0002-z

Cited by 3 publications

(3 citation statements)

References 2 publications

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“…The latest non-contact techniques aim to optimize the ink deposition methods and reduce the dimensions. Moreover, the sintering methods are below examination for optimizing ink post methods [45,46]. These techniques face challenges, including repeatability, conductivity, and the standardization that still affects printed electronics-based biosensors when checked with the bulk partners.…”

Section: Biosensors and Printed Electronics-based Biosensorsmentioning

confidence: 99%

Printed electronics-based biosensors

SAYLAN,

KILIÇ,

DENİZLİ

2024

Hacettepe Journal of Biology and Chemistry

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Printed electronics have attracted enormous interest owing to their large production capability, low cost, and environmentally friendly properties. Printed electronics-based biosensors have also achieved increasing attention in different domains that range from laboratory to home for many applications. They will be necessary for the implementation of next-generation platforms due to printing simplifies the fabrication of platforms on several thin, rigid, and/or flexible substrates. Moreover, the printed electronics-based biosensors show an excellent chance to facilitate fast, sensitive, and real-time screening of several molecules to exploit their features. Printing technology has strong impacts to assemble more customizable and simpler production of biosensors with great resolution and combination with microfluidic and electronics systems. This review is a summary of recent progress in printed electronics-based biosensors to produce various electronic devices and circuits and also supplies a review of the properties of printed electronics-based biosensors in different applications. In the end, up-to-date experiments of the latest studies of the printed electronics-based biosensors for various target molecules is reported.

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Section: Biosensors and Printed Electronics-based Biosensorsmentioning

confidence: 99%

Printed electronics-based biosensors

SAYLAN,

KILIÇ,

DENİZLİ

2024

Hacettepe Journal of Biology and Chemistry

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“…Liquid (conductive) materials can be applied through various methods, for example, contactless methods such as ink-jetting or aerosol jetting [25]. However, the contactless dosing of particle-filled fluids such as ICA is complex and special dosing valves are required.…”

Section: Fff Printer Customizationmentioning

confidence: 99%

A Printing Strategy for Embedding Conductor Paths into FFF Printed Parts

Banko,

Grünwald,

Kronberger

et al. 2023

Polymers

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A novel approach to manufacture components with integrated conductor paths involves embedding and sintering an isotropic conductive adhesive (ICA) during fused filament fabrication (FFF). However, the molten plastic is deposited directly onto the adhesive path which causes an inhomogeneous displacement of the uncured ICA. This paper presents a 3D printing strategy to achieve a homogeneous cross-section of the conductor path. The approach involves embedding the ICA into a printed groove and sealing it with a wide extruded plastic strand. Three parameter studies are conducted to obtain a consistent cavity for uniform formation of the ICA path. Specimens made of polylactic acid (PLA) with embedded ICA paths are printed and evaluated. The optimal parameters include a groove printed with a layer height of 0.1 mm, depth of 0.4 mm, and sealed with a PLA strand of 700 µm diameter. This resulted in a conductor path with a homogeneous cross-section, measuring 660 µm ± 22 µm in width (relative standard deviation: 3.3%) and a cross-sectional area of 0.108 mm2 ± 0.008 mm2 (relative standard deviation 7.2%). This is the first study to demonstrate the successful implementation of a printing strategy for embedding conductive traces with a homogeneous cross-sectional area in FFF 3D printing.

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“…Along with the advantages discussed, challenges in terms of compatibility among the wide variety of materials used in the fabrication of sensors represent a predominant issue that must be faced to ensure the feasibility and metrological performances of the printed devices. The most recent emerging non-contact techniques [46] are aiming to optimize the processes of ink deposition, reducing the dimensions of droplets (micro-or nano-pen printings [47,48]), through the finest control of printed track width using lasers (LIFT) or by focusing aerosol ink through a stream of gas (AJP) [49]. Additionally, novel sintering methods (e.g., photonic curing) are under investigation to optimize ink post-processing.…”

Section: Introductionmentioning

confidence: 99%

Printed Electrochemical Biosensors: Opportunities and Metrological Challenges

2020

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Printed electrochemical biosensors have recently gained increasing relevance in fields ranging from basic research to home-based point-of-care. Thus, they represent a unique opportunity to enable low-cost, fast, non-invasive and/or continuous monitoring of cells and biomolecules, exploiting their electrical properties. Printing technologies represent powerful tools to combine simpler and more customizable fabrication of biosensors with high resolution, miniaturization and integration with more complex microfluidic and electronics systems. The metrological aspects of those biosensors, such as sensitivity, repeatability and stability, represent very challenging aspects that are required for the assessment of the sensor itself. This review provides an overview of the opportunities of printed electrochemical biosensors in terms of transducing principles, metrological characteristics and the enlargement of the application field. A critical discussion on metrological challenges is then provided, deepening our understanding of the most promising trends in order to overcome them: printed nanostructures to improve the limit of detection, sensitivity and repeatability; printing strategies to improve organic biosensor integration in biological environments; emerging printing methods for non-conventional substrates; microfluidic dispensing to improve repeatability. Finally, an up-to-date analysis of the most recent examples of printed electrochemical biosensors for the main classes of target analytes (live cells, nucleic acids, proteins, metabolites and electrolytes) is reported.

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Reproducible Dispensing of Liquids in the Nanolitre Range

Cited by 3 publications

References 2 publications

Printed electronics-based biosensors

Printed electronics-based biosensors

A Printing Strategy for Embedding Conductor Paths into FFF Printed Parts

Printed Electrochemical Biosensors: Opportunities and Metrological Challenges

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