Abstract:Introduction
To study the efficacy of novel regenerative strategies is necessary to develop new models that do not implement annulus fibrosus (AF) damage. We hypothesize an ideal preclinical model to study novel biological therapies for nucleus pulpous (NP) regeneration can be achieved by approaching the NP via the endplate (EP) route through a minimal invasive transpedicular approach.1 The aim of the study is to characterize a preclinical ovine model triggering EP damage and repair with or without mechanical … Show more
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