Reproducibility of the Optic Nerve Head Topography with a New Laser Tomographic Scanning Device

Rohrschneider, Klaus; Burk, Reinhard; Kruse, Friedrich E.; Völcker, H. E.

doi:10.1016/s0161-6420(94)31220-6

Cited by 232 publications

(111 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Previous reports have employed the coefficient of variation 7,12,17,19,29 for expressing measurement precision. Unfortunately, it is a relative measure of precision; therefore, it cannot be directly applied as a diagnostic tool in disease detection and follow-up over time.…”

Section: Discussionmentioning

confidence: 99%

“…So far, SLO-studies have mainly evaluated the usefulness of optic disc parameters for glaucoma detection, their reproducibility of measurements and any correlations with visual field defects. [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] However, relatively little attention has been paid to the possible value of SLO optic disc biometry for improvement of glaucoma follow-up. [20][21][22] To reliably detect development or progression of disease with a certain measurement parameter, it is necessary to know the absolute difference between follow-up measurements that must be exceeded to detect a statistically significant change over time.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Estimating the clinical usefulness of optic disc biometry for detecting glaucomatous change over time

Tangelder

Reus

Lemij

2005

Eye

View full text Add to dashboard Cite

Purpose First, to determine the absolute measurement precision of scanning laser ophthalmoscopy (SLO) parameters, by expressing them as 95% limits of agreement (LA 95% ). Second, to propose a method for mathematically estimating the clinical ability of a parameter to monitor disease progression, expressed as the Discriminating Capacity Index (DCI). Methods We measured the optic disc of 14 healthy volunteers and 14 glaucoma patients. LA 95% -values were calculated from the average standard deviation of three measurements on the same day for repeatability, and three measurements on separate days within a 6-week period for reproducibility. We then calculated the DCI by dividing the measurement range by its LA 95% in healthy subjects and glaucoma patients separately. Thus, the DCI takes into account both the dynamic range of disease progression and the extent of measurement variance, providing an index of the possible clinical usefulness of a parameter. As the DCI is dimensionless it allows comparison across various parameters and across technologies.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Estimating the clinical usefulness of optic disc biometry for detecting glaucomatous change over time

Tangelder

Reus

Lemij

2005

Eye

View full text Add to dashboard Cite

show abstract

“…This technique has been described in detail elsewhere. 9,10 Disc area was defined as the total area within the contour line. Rim area was defined as the area within the contour line and above the reference plane.…”

Section: Methodsmentioning

confidence: 99%

Is the ISNT rule violated in early primary open-angle glaucoma—a scanning laser tomography study

Sihota

Srinivasan

Dada

et al. 2007

Eye

View full text Add to dashboard Cite

Aims To evaluate the relevance of the ISNT rule with reference to the optic nerve head, in differentiating normal and early glaucoma eyes and neuroretinal rim (NRR) area ratios as measures of glaucomatous optic neuropathy by confocal scanning laser ophthalmoscopy (Heidelberg retina tomography (HRT) II). Methods The study included 136 control eyes and 63 eyes of early primary open-angle glaucoma. Each patient underwent a complete ophthalmic examination, HRT II (software 2.01) and achromatic automated perimetry using the Humphrey field analyzer Full threshold program 30-2 or 24-2. Topographic HRT parameters (disc area and rim area) were compared between the groups. To assess the statistical significance of differences between the study groups, the Student's t-test was used. Results The ISNT rule was applicable in 71% of normal eyes and 68% of early glaucoma eyes. The superior to inferior area ratio was 0.9670.01 in the normal group and 0.9070.02 in the glaucoma group. There was a loss of approximately a quarter of the NRR in the inferotemporal and superotemporal quadrants. The inferonasal sector showed the least loss of NRR (4.34%). Conclusion The inferior NRR is marginally wider than the superior NRR in about 2/3 of normal eyes, but could not be clinically appreciated in many of these. The characteristic configuration of a normal optic disc with the rim width being greatest in the inferior disc region followed by the superior disc region was maintained even in most patients with early glaucoma.

show abstract

“…Oftalmoskopi ve fundus foto¤rafik incelemeleri glokomatöz optik disk hasar›n›n de¤erlendirilmesinde halen yayg›n olarak kullan›lsa da subjektif ve niteleyici özellik tafl›d›klar›ndan hatalar ve eksiklikler gözlenebilmektedir (7). Konfokal scanning lazer oftalmoskop olan Heidelberg Retinal Tomografi (HRT) gibi yöntemler optik diskin objektif, üç boyutlu niceleyici ve tekrarlanabilen özellikteki de¤erlendi-rilmesine olanak sa¤lamaktad›r (5,(8)(9)(10)(11).…”

Section: Giriflunclassified

A Comparison of Optic Disc Topographic Parameters in Primary Open-Angle Glaucoma Cases with or without Family History of Glaucomai

Şen¹,

Kara²,

Elgin³

et al. 2010

tod

View full text Add to dashboard Cite

ÖzetAmaç: Aile hikayesi olan ve olmayan primer aç›k aç›l› glokom (PAAG) olgular›n›n tan› esnas›ndaki optik disk topografik de¤erlerinin k›yaslanmas›. Gereç ve Yöntem: Aile hikayesi olan (26 hasta, 52 göz) ve olmayan (28 hasta, 56 göz) PAAG olgular›, geriye dönük olarak incelendi. Tüm hastalar›n düzeltilmifl görme keskinli¤i, biyomikroskopik, fundus ve gonyoskopik muayeneleri, Goldmann aplanasyon tonometresi ile göziçi bas›nc› (G‹B) de¤erleri, Heidelberg Retinal Tomografi (HRT) III ile optik disk topografi analizleri, Humphrey otomatize perimetri ile görme alan› incelemeleri ve ultrasonik pakimetri ile merkezi kornea kal›nl›k (MKK) de¤erleri kaydedildi. ‹statistiksel yöntem olarak Mann-Whitney U testi, ki kare ve t test kullan›ld›. Sonuçlar: Ailesinde glokom hikayesi pozitif olan grup ile olmayan grup aras›nda; yafl, cinsiyet, MKK, G‹B, HRT III parametreleri aç›s›ndan fark saptanmad›. Tan› esnas›ndaki yafl ortalamas› aile hikayesi pozitif olan grupta 48,1±8,6, olmayan grupta ise 56,4±10,9 idi. Aile hikayesi olan olgularda yafl anlaml› olarak daha genç bulundu (p:0,003). Tart›flma: Aile hikayesi olan ve olmayan PAAG hastalar›nda tan› esnas›nda optik disk topografik parametreleri aras›nda fark tesbit edilmemifltir. Ancak aile hikayesi olan PAAG olgular›nda daha erken yaflta tan› konuldu¤u gözlenmifltir. (TOD Dergisi 2010; 40: 205-8) Anahtar Kelimeler: Aile hikayesi, Heidelberg retinal tomografi, optik disk topografisi, primer aç›k aç›l› glokom Summary Purpose: To compare the optic disc topographic parameters of primary open-angle glaucoma (POAG) cases with or without family history of the disease. Materia and Method: Cases of POAG, with (26 cases, 52 eyes) or without (28 cases, 56 eyes) family history of glaucoma, were investigated retrospectively. The following results were recorded: best-corrected visual acuity, slit-lamp, fundus, gonioscopic and perimetric examinations, intraocular pressure (IOP) measured by Goldmann applanation tonometer, analysis of optic disc topography by Heidelberg Retina Tomograph (HRT III), and central corneal thickness (CCT) using ultrasonic pachymeter. Mann-Whitney U, chi-square and t-tests were used for statistical analysis. Results: No statistically significant differences in terms of sex, CCT, IOP, and HRT III parameters were observed between the patients with or without family history of glaucoma. The mean age at the time of glaucoma diagnosis was 48.1±8.6 in the subjects with family history of glaucoma and, 56.4±10.9 in those without family history of the disease. The cases with family history were significantly younger at the time of glaucoma diagnosis than those without family history (p: 0.003). Discussion: No differences were detected between the optic disc topographic parameters of the POAG cases with and without family history, whereas it was observed that the POAG cases with positive family history were younger at the time of glaucoma diagnosis. (TOD Journal 2010; 40: 205-8)

show abstract

Reproducibility of the Optic Nerve Head Topography with a New Laser Tomographic Scanning Device

Cited by 232 publications

References 12 publications

Estimating the clinical usefulness of optic disc biometry for detecting glaucomatous change over time

Estimating the clinical usefulness of optic disc biometry for detecting glaucomatous change over time

Is the ISNT rule violated in early primary open-angle glaucoma—a scanning laser tomography study

A Comparison of Optic Disc Topographic Parameters in Primary Open-Angle Glaucoma Cases with or without Family History of Glaucomai

Contact Info

Product

Resources

About