Reproducibility of radial pulse wave analysis in healthy subjects

Filipovský, Jan; Svobodová, Vlasta; Pecen, Ladislav

doi:10.1097/00004872-200018080-00007

Cited by 91 publications

(73 citation statements)

References 14 publications

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“…14,15 This new technique is reproducible, noninvasive and increasingly used in clinical studies. 31,32 Both measures are closely correlated, 16,33 and PWV is an important determinant of augmentation index. However, both measures were derived using methods that are technically completely independent from each other.…”

Section: Discussionmentioning

confidence: 99%

The T-allele of the C825T polymorphism is associated with higher arterial stiffness in young healthy males

et al. 2004

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Section: Discussionmentioning

confidence: 99%

The T-allele of the C825T polymorphism is associated with higher arterial stiffness in young healthy males

et al. 2004

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“…AI in the aorta measured non-invasively by PWA is considered a reliable and reproducible marker [20][21][22] to assess the current status of the cardiovascular system. Its values reflect the timing of reflected pressure waves returning to the aorta and therefore aortic pulse wave velocity and arterial stiffness 23,24 as well as changes associated with the intensity of the reflected waves which depends on the vascular tone and properties of the small muscular arteries/ arterioles.…”

Section: Discussionmentioning

confidence: 99%

The combined effect of augmentation index and carotid intima-media thickness on cardiovascular risk in young and middle-aged men without cardiovascular disease

et al. 2006

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Carotid artery intima-media thickness (IMT) has been used as a surrogate marker of atherosclerosis and is related to cardiovascular risk. Indices of arterial stiffness are also associated with cardiovascular risk and atherosclerosis. The aim of this study was to assess the prognostic value of the combination of surrogate markers of cardiovascular disease measured non-invasively in subjects without cardiovascular disease. In this cross-sectional study, 81 young and middle aged males (39.276.3 years) without evidence of overt cardiovascular disease or diabetes mellitus were enrolled. Highresolution B-mode ultrasonography and pulse wave analysis were used to measure carotid artery IMT and augmentation index (AI), a measure of arterial stiffness. Framingham risk score (FRS) was used as an estimate of the risk for development of cardiovascular disease. Regional differences were observed in the carotid arteries' IMT regarding their relationship with FRS: combined (average from all sites) IMT and IMT in the carotid bulb (CB), but not in the common (CC) and internal carotid artery (IC), and AI showed significant increases of FRS by their tertiles. However, subjects with both AI and IMT at any site in the highest tertile (AI415%, CC40.65 mm, CB40.8 mm, IC40.65 mm) had an increased FRS compared to subjects with one or none of these parameters in the highest tertile. In conclusion, young and middle-aged men without overt cardiovascular disease with both high IMT and AI are in high cardiovascular risk, as assessed by FRS. Epidemiological studies are needed to further validate this combination.

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“…[16] Using magnitude-based inference [17] to estimate the sample size required to detect the smallest beneficial (or detrimental) in a cross-over study, with the maximum chances of a type 1 and 2 error set at 5% (i.e., very unlikely), approximately 8 participants are required to detect a 6 mmHg change (based on the smallest change reported in previous blood pressure studies. [18] We oversampled to account for the uncertainty with regards to the effect of fasting.…”

Section: Reliability Of Waveform Separation Analysismentioning

confidence: 99%

Reliability of pulse waveform separation analysis

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Fryer

et al. 2017

Journal of Hypertension

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Reproducibility of radial pulse wave analysis in healthy subjects

Cited by 91 publications

References 14 publications

The T-allele of the C825T polymorphism is associated with higher arterial stiffness in young healthy males

The T-allele of the C825T polymorphism is associated with higher arterial stiffness in young healthy males

The combined effect of augmentation index and carotid intima-media thickness on cardiovascular risk in young and middle-aged men without cardiovascular disease

Reliability of pulse waveform separation analysis

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