Reproducibility of electronic Von Frey and Von Frey monofilaments testing

Intradermal Injection with Nerve Growth Factor: A Reproducible Model to Induce Experimental Allodynia and Hyperalgesia

“…For example, the thermode heat pain model is well known and has been widely used in both basic as well as clinical studies and has proven valid and reproducible . Similarly, a recent study by Tena and colleagues investigated the reproducibility of von Frey filaments across different time points and across different observers . Pressure algometry as a model of experimental pain has been used extensively in the literature, and several studies have investigated and approved its reproducibility .…”

Test Procedures to Assess Somatosensory Abnormalities in Individuals with Peripheral Joint Pain: A Systematic Review of Psychometric Properties

“…In knee OA, 2 separate studies assessed reliability of mechanical detection threshold (light touch), and a further 2 assessed the reliability of CPM in patients with knee OA and in different shoulder disorders (Tables and ) . Single studies assessed the reliability of the warm detection threshold, cold detection threshold, and heat pain threshold in patients with knee OA; reliability of heat/cold pain thresholds in patients with subacute ankle sprain; reliability of cold allodynia in patients with knee OA; and reliability of mechanical hyperalgesia in patients with knee pain following knee arthroplasty …”

“…Of the 14 reliability studies assessed using the QAREL tool, only 7 studies scored high methodological quality: 5 investigated patients with knee pain, 1 assessed patients with ankle pain, and 1 assessed patients with elbow pain (Table ) . The majority of reliability studies scored “poor” methodological quality using the COSMIN tool.…”

“…Specific training for clinicians in administration of QST and participants’ familiarization with these stimuli and response procedures are essential factors to avoid results bias . Only 6 studies reported training of investigators prior to the trials, while 4 studies included a session to familiarize participants with test procedures . Therefore, it may be necessary for future research to provide training sessions for assessors to ensure consistency of test procedures and to avoid applicator or results bias.…”