Repressor elements provide insights into tissue development and phenotypes in the pig
Yue-Dong Zhang,
Chao Guo,
Hang Liu
et al.
Abstract:Repressor elements play important roles in economic phenotypes of the pig, however, these elements remain poorly characterized. Here, we used H3K27me3, ATAC-seq and RNA-seq data derived from six tissues from three embryonic layers to identify 2 034 super repressor elements (SREs) and 22 223 typical repressor elements (TREs) in the pig genome. Among the identified repressor elements, many are shared by mesodermal and ectodermal tissues. SREs tightly regulate their target genes (within a specific genomic region,… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.