Representation of Olfactory Information in Organized Active Neural Ensembles in the Hypothalamus

Carvalho, Vinicius Miessler de Andrade; Nakahara, Thiago Seike; Souza, Mateus Augusto de Andrade; Cardozo, Leonardo Minete; Trintinalia, Guilherme Ziegler; Pissinato, Leonardo Granato; Stowers, Lisa; Papes, Fábio

doi:10.1016/j.celrep.2020.108061

Cited by 23 publications

(26 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition to their role in controlling mating behaviors, VMHvl neurons may play a role in responding to cues from conspecifics (as opposed to the animal's own behavior). The VMH receives inputs from MeA neurons carrying information about odorants (Choi et al, 2005;Carvalho et al, 2020).…”

Section: Ventromedial Hypothalamusmentioning

confidence: 99%

“…In addition to their role in controlling mating behaviors, VMHvl neurons may play a role in responding to cues from conspecifics (as opposed to the animal’s own behavior). The VMH receives inputs from MeA neurons carrying information about odorants ( Choi et al, 2005 ; Carvalho et al, 2020 ). Projections from somatosensory cortex to the VMH have also been identified by tracing ( Stanzani and Russo, 1980 ), but functional responses from these projections have not been recorded.…”

Section: Neural Circuitry For Integration Of Social Signalsmentioning

confidence: 99%

See 1 more Smart Citation

Cupid’s quiver: Integrating sensory cues in rodent mating systems

Hoglen

Manoli

2022

Front. Neural Circuits

View full text Add to dashboard Cite

In many animal species, males and females exploit different mating strategies, display sex-typical behaviors, and use distinct systems to recognize ethologically relevant cues. Mate selection thus requires mutual recognition across diverse social interactions based on distinct sensory signals. These sex differences in courtship and mating behaviors correspond to differences in sensory systems and downstream neural substrates engaged to recognize and respond to courtship signals. In many rodents, males tend to rely heavily on volatile olfactory and pheromone cues, while females appear to be guided more by a combination of these chemosensory signals with acoustic cues in the form of ultrasonic vocalizations. The mechanisms by which chemical and acoustic cues are integrated to control behavior are understudied in mating but are known to be important in the control of maternal behaviors. Socially monogamous species constitute a behaviorally distinct group of rodents. In these species, anatomic differences between males and females outside the nervous system are less prominent than in species with non-monogamous mating systems, and both sexes engage in more symmetric social behaviors and form attachments. Nevertheless, despite the apparent similarities in behaviors displayed by monogamous males and females, the circuitry supporting social, mating, and attachment behaviors in these species is increasingly thought to differ between the sexes. Sex differences in sensory modalities most important for mate recognition in across species are of particular interest and present a wealth of questions yet to be answered. Here, we discuss how distinct sensory cues may be integrated to drive social and attachment behaviors in rodents, and the differing roles of specific sensory systems in eliciting displays of behavior by females or males.

show abstract

Section: Ventromedial Hypothalamusmentioning

confidence: 99%

Section: Neural Circuitry For Integration Of Social Signalsmentioning

confidence: 99%

Cupid’s quiver: Integrating sensory cues in rodent mating systems

Hoglen

Manoli

2022

Front. Neural Circuits

View full text Add to dashboard Cite

show abstract

“…Male urinary chemosignals stimulate the accessory olfactory system via the amygdala and the bed nucleus of the stria terminalis and activate the dopaminergic neurons in the ventral premammillary nucleus, a crucial site for selecting the behavioral response to specific sex-related chemosignals (Chen et al 2020). However, a strict spatial localization of the implementation of behavioral patterns in response to chemical signals is not clearly emerging within the hypothalamus (Carvalho et al 2020).…”

Section: The Hypothalamus As a Site Of Neuro-hormonal Integrationmentioning

confidence: 99%

Processing of intraspecific chemical signals in the rodent brain

Mucignat‐Caretta

2021

Cell Tissue Res

View full text Add to dashboard Cite

In the rodent brain, the central processing of ecologically relevant chemical stimuli involves many different areas located at various levels within the neuraxis: the main and accessory olfactory bulbs, some nuclei in the amygdala, the hypothalamus, and brainstem. These areas allow the integration of the chemosensory stimuli with other sensory information and the selection of the appropriate neurohormonal and behavioral response. This review is a brief introduction to the processing of intraspecific chemosensory stimuli beyond the secondary projection, focusing on the activity of the relevant amygdala and hypothalamic nuclei, namely the medial amygdala and ventromedial hypothalamus. These areas are involved in the appropriate interpretation of chemosensory information and drive the selection of the proper response, which may be behavioral or hormonal and may affect the neural activity of other areas in the telencephalon and brainstem. Recent data support the notion that the processing of intraspecific chemical signals is not unique to one chemosensory system and some molecules may activate both the main and the accessory olfactory system. Moreover, both these systems have mixed projections and cooperate for the correct identification of the stimuli and selection of relevant responses.

show abstract

“…In rodents, anterior medial amygdala (MeA dorsal and ventral; MeAd/v) receives most of the direct vomeronasal and main olfactory input. MeA relays information to posterior medial amygdala (MeP; dorsal and ventral; MePd/v) and both MeA and MeP have projections to basal forebrain regions, including preoptic area and hypothalamus, which are essential for normal reproductive and social behavior ( Been and Petrulis, 2011 , Carvalho et al, 2020 , Coolen and Wood, 1998 , Keshavarzi et al, 2014 , Kondo and Arai, 1995 , Wang et al, 2013 ). Amygdala processing is subject to modulation by dopamine ( Gregoriou et al, 2019 , Marowsky et al, 2005 ), which can act via GABA input from the intercalated nuclei.…”

Section: Introductionmentioning

confidence: 99%

Representation of Olfactory Information in Organized Active Neural Ensembles in the Hypothalamus

Cited by 23 publications

References 53 publications

Cupid’s quiver: Integrating sensory cues in rodent mating systems

Cupid’s quiver: Integrating sensory cues in rodent mating systems

Processing of intraspecific chemical signals in the rodent brain

Functional connectivity of intercalated nucleus with medial amygdala: A circuit relevant for chemosignal processing

Contact Info

Product

Resources

About