Abstract:II
ABSTRACTThe diversity and multi-functionality of cellular lipids is astounding. At the hub of phospho-and neutral lipid flux are two lipids with many effector proteins: diacylglycerol (DAG) and phosphatidic acid (PA). Enzymes which can simultaneously regulate both of their levels are diacylglycerol kinases (DGKs) and lipins. The former phosphorylates DAG to yield PA and the latter dephosphorylates PA to generate DAG. The work herein approaches the study of DGKs and lipins from two different perspectives.Fir… Show more
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