Reported Calcium Intake is Reduced in Women with Preeclampsia

Ramos, José Geraldo Lopes; Brietzke, Elisa; Costa, Sérgio Hofmeister de Almeida Martins; Vettorazzi, Janete; Barros, Elvino; Carvalho, Clarissa Gutiérrez

doi:10.1080/10641950600913008

Cited by 16 publications

(11 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Four studies [ 20 , 26 , 35 , 36 ] reporting on the association between nutrient intake and both mild and severe pre-eclampsia were included as four separate results in meta-analyses. Another study [ 22 ] reported on dietary intake at 11–15, 26, and 34–37 weeks’ gestation.…”

Section: Resultsmentioning

confidence: 99%

“…Of seven case–control studies [ 21 , 25 , 27 , 28 , 35 , 55 , 56 ] and six cohort studies [ 20 , 22 , 42 , 43 , 45 , 50 ] reporting on unadjusted calcium intake in HDP cases and non-cases, three case–control studies [ 28 , 55 , 56 ] and seven cohort studies [ 20 , 22 , 35 , 42 , 43 , 45 , 50 ] could be included in the meta-analysis (Figure 4 a and b, respectively). Results from case–control studies consistently showed lower reported calcium intake for HDP cases compared with non-cases, but the pooled result was not statistically significant (WMD = −39.89, 95% CI −109.52 to 29.75; I 2 36.6%; P = 0.21).…”

Section: Resultsmentioning

confidence: 99%

“…The presence of random and systematic measurement errors in self-reported dietary intake could attenuate the associations found, and reduce the statistical power to detect an association. In addition, timing of dietary assessment was not prior to, but at or after diagnosis in case–control studies [ 21 , 23 , 25 , 27 , 28 , 36 , 52 - 60 ] and two retrospective cohort studies [ 35 , 49 ], which may have caused recall bias. Additionally, dietary assessment methods differed between studies (FFQs, dietary interviews, recalls, or records).…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, HDP are heterogeneous, and there may be etiological differences according to severity and timing of onset between disorders; however, few studies reported results for these subtypes separately. Four studies examining subtypes suggested a more pronounced risk for severe compared with mild pre-eclampsia for lower intake of calcium [ 35 ], vitamin C [ 26 ], and probiotics [ 20 ], and higher consumption of tea [ 36 ]. Clausen et al found a significant trend towards increasing intake of energy and sucrose across categories without pre-eclampsia, late-onset pre-eclampsia, and early-onset pre-eclampsia [ 40 ].…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

The association between dietary factors and gestational hypertension and pre-eclampsia: a systematic review and meta-analysis of observational studies

Schoenaker

Soedamah‐Muthu

Mishra

2014

BMC Med

107

102

View full text Add to dashboard Cite

BackgroundDietary factors have been suggested to play a role in the prevention of hypertensive disorders of pregnancy (HDP), including gestational hypertension and pre-eclampsia, but inconsistent findings have been reported. A systematic review and meta-analyses were performed to synthesize evidence from observational studies of reproductive-aged women on the association between dietary factors and HDP.MethodsMEDLINE and EMBASE were searched to identify studies published until the end of May 2014. Studies were included if they were observational studies of reproductive-age women and reported results on dietary factors (energy, nutrients, foods or overall dietary patterns, alone or in combination with dietary supplements) and gestational hypertension and/or pre-eclampsia. Studies were excluded if they reported on supplements not in combination with dietary intake, or examined a biomarker of dietary intake. Random effects meta-analyses were performed on calculated weighted mean differences (WMD) of dietary intake between cases and non-cases, and effect estimates were pooled.ResultsIn total, 23 cohort and 15 case–control studies were identified for systematic review, of which 16 could be included in the meta-analyses. Based on meta-analyses of cohort studies, unadjusted energy intake was higher for pre-eclampsia cases (WMD 46 kcal/day, 95% confidence interval (CI) −13.80 to 106.23; I2 = 23.9%, P = 0.26), although this was not statistically significant. Unadjusted intakes of magnesium (WMD 8 mg/day, 95% CI −13.99 to −1.38; I2 = 0.0%, P = 0.41) and calcium (WMD 44 mg/day, 95% CI −84.31 to −3.62, I2 = 51.1%, P = 0.03) were lower for the HDP cases, compared with pregnant women without HDP. Higher calcium intake consistently showed lower odds for HDP after adjustment for confounding factors (OR = 0.76, 95% CI 0.57 to 1.01, I2 = 0.0%, P = 0.79). A few studies examining foods and dietary patterns suggested a beneficial effect of a diet rich in fruit and vegetables on pre-eclampsia, although not all the results were statistically significant.ConclusionsBased on a limited number of studies, higher total energy and lower magnesium and calcium intake measured during pregnancy were identified as related to HDP. Further prospective studies are required to provide an evidence base for development of preventive health strategies, particularly focusing on dietary factors during pre-pregnancy and early pregnancy.Please see related article: http://www.biomedcentral.com/1741-7015/12/176/abstract.Electronic supplementary materialThe online version of this article (doi:10.1186/s12916-014-0157-7) contains supplementary material, which is available to authorized users.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

The association between dietary factors and gestational hypertension and pre-eclampsia: a systematic review and meta-analysis of observational studies

Schoenaker

Soedamah‐Muthu

Mishra

2014

BMC Med

107

102

View full text Add to dashboard Cite

show abstract

“…Smith et al more recently demonstrated that the MDRD2 formula also underestimated measured GFR in both healthy and preeclamptic pregnancies (23). The agreement between the Cockcroft-Gault, MDRD2 and 24-hour CrCl in women with a hypertensive disorder of pregnancy has also been found to be suboptimal[24]. While endogeneous markers of GFR, such as cystatin-C or beta trace protein, have been studied in pregnancy, they do not appear to reliably reflect renal function in this population (25,26).…”

Section: Discussionmentioning

confidence: 99%

A Comparison of Prediction Equations for Estimating Glomerular Filtration Rate in Pregnancy

Ahmed¹,

Bentley‐Lewis²,

Hollenberg³

et al. 2009

Hypertension in Pregnancy

View full text Add to dashboard Cite

Objective To compare existing glomerular filtration rate (GFR) prediction equations with the gold standard, inulin clearance, in pregnancy. Methods Five equations were assessed for precision, bias, and accuracy in prediction of true GFR, measured by inulin clearance in 12 healthy, pregnant women during the second (T2) and third (T3) trimesters and in postpartum (PP). Results Precision was greatest with 24-hour creatinine clearance estimation of GFR (R2 = 13% (T2), R2 = 26% (T3)). Other than 100/SCr, all equations underestimated true GFR. 30% accuracy was greatest in 100/SCr (83% (T2), 92% (T3)). Conclusions Current GFR prediction formulae do not appear to be sufficient for estimating GFR in the gravid state.

show abstract

Analysis of serum calcium, sodium, potassium, zinc, and iron in patients with pre‐eclampsia in Bangladesh: A case–control study

Uddin

Haque

Barek

et al. 2023

Health Science Reports

View full text Add to dashboard Cite

Background and Aims Pre‐eclampsia is a particular type of pregnancy condition. Although the primary etiology of pre‐eclampsia is unclear, it hypothesizes that the alteration of trace elements and macro‐minerals may play a crucial function in the pathogenesis of Pre‐eclampsia. Therefore, our research sought to ascertain the serum level of trace elements (zinc, iron) and macro‐minerals (sodium, calcium, potassium) and their possible association with pre‐eclampsia. Methods The present study was conducted with 74 pre‐eclampsia pregnant women (case) and 118 pregnant women having normal blood pressure (controls). Atomic Absorption Spectroscopy determined the serum level of trace components and electrolytes. Results The researchers discovered notable differences in maternal age, gestational period, body mass index, systolic and diastolic blood pressure, hemoglobin, and creatinine level. Results of serum analysis revealed that calcium (52.06 ± 3.71 mg/L vs. 65.93 ± 2.57 mg/L, p < 0.05) and potassium (63.44 ± 5.33 mg/L vs. 102.54 ± 4.25 mg/L, p < 0.001) concentrations were substantially lower in the patient group than in control. Serum zinc (0.34 ± 0.02 mg/L vs. 0.52 ± 0.02 mg/L, p < 0.001) and iron (0.38 ± 0.03 mg/L vs. 0.46 ± 0.02 mg/L, p < 0.05) concentration were also considerably decreased in pre‐eclampsia participants compared with a pregnant normotensive group. Pearson's correlation research results in the patient group revealed a connection between trace elements or macro minerals. In addition, the systolic blood pressure was positively correlated with sodium ( r = 0.392, p < 0.01) and negatively correlated with potassium ( r = −0.257, p < 0.05) in the control group. Conclusions This study concludes that calcium, potassium, iron, and zinc levels were lower, whereas sodium levels were higher in Bangladeshi pre‐eclampsia patients compared to controls. These findings with Pearson's correlation and the inter‐element relationship between the patient and a control subject results can act as critical indication factors for patients with pre‐eclampsia in Bangladesh and, as a result, may require a higher intake of calcium, potassium, iron, and zinc for effective therapeutic intervention and reduce the intake of sodium.

show abstract

Reported Calcium Intake is Reduced in Women with Preeclampsia

Abstract: The results of the present study can provide the foundations for prospective trials, including randomised clinical trials involving only patients with a low content of calcium in their diet.

Cited by 16 publications

References 11 publications

The association between dietary factors and gestational hypertension and pre-eclampsia: a systematic review and meta-analysis of observational studies

The association between dietary factors and gestational hypertension and pre-eclampsia: a systematic review and meta-analysis of observational studies

A Comparison of Prediction Equations for Estimating Glomerular Filtration Rate in Pregnancy

Analysis of serum calcium, sodium, potassium, zinc, and iron in patients with pre‐eclampsia in Bangladesh: A case–control study

Contact Info

Product

Resources

About