Report of Bilateral Microtia in 2 Successive Female Siblings in Fallujah General Hospital

Abstract

Microtia is a congenital anomaly; characterized by a small, abnormally shaped auricle (pinna). It is usually accompanied by a narrow, blocked or absent ear canal. Microtia can occur as the only clinical abnormality or as part of a syndrome. The estimated incidence of microtia is (1 / 5000) to (1/ 20000) of total births and it is more common in males. Microtia can have a genetic or environmental predisposition. Here we reported a family with 2 successive deliveries of female infants within 12 months period, with bilateral microtia in the absence of any of the known risk factors or teratogens, in addition to the absence of previous family history of any kind of birth anomalies.

Bioinformatics analysis of microRNA comprehensive regulatory network in congenital microtia

“…Microtia is a congenital malformation of the external ear, characterized by a small, abnormally shaped auricle [1,2]. This disease occurs in 1 out of about 8000-10,000 births with phenotypes ranging from minor deformities to complete absence of the external ear [3].…”

“…This disease occurs in 1 out of about 8000-10,000 births with phenotypes ranging from minor deformities to complete absence of the external ear [3]. Microtia can be unilateral or bilateral, while unilateral microtia usually has normal hearing in the other ear [1].…”

Demographic Factors Associated with Congenital Malformations Among Young Infants in Fallujah Maternity and Children Hospital, Fallujah City, Iraq

“…The unit involves fetal medicine clinic, clinical genetics clinic, pediatric cardiology clinic, chromosomal laboratory and a unit for registration, documentation, data analysis and research studies. The unit issued several research studies and case reports, proving the existence of a striking increase in the incidence and severity of birth defects for children born after the year 2005 [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17].…”