Report of a Case of Pancreatic Hamartoma

Pancreatic hamartoma: Possibility of a preoperative diagnosis via endoscopic ultrasound–guided fine‐needle aspiration biopsy

“…However, diagnosis is sometimes difficult owing to the small sample size. Although the findings of preoperative EUS-FNA have been reported in 13 cases in the English literature and 4 cases in the Japanese literature, [2][3][4]6,7,[9][10][11][12][13][14][15] none were preoperatively diagnosed with pancreatic hamartoma (Supplementary Table 1, online resource) because it comprises mature pancreatic tissue and clinicians and pathologists are unfamiliar with this disease. 3 Unfortunately, our patient was not diagnosed preoperatively.…”

“…Pancreatic hamartoma is a very rare, non‐neoplastic, mass‐forming pancreatic lesion, 1 with only 64 cases reported in the English literature and 7 in the Japanese literature, without abstract only (based on literature searches using the PubMed and Japanese Ichushi databases) 1–51 . As pancreatic hamartoma is typically asymptomatic, in more than half the abovementioned reports, the cases has been incidentally discovered 1–51 . Furthermore, preoperative diagnosis using various techniques, such as CT, MRI, or US, is extremely difficult because various neoplasms, such as NET, solid pseudopapillary neoplasm, and adenocarcinoma, are included in the differential diagnosis, as described in the case report and literature review by Noguchi et al 1 In our case, the imaging findings suggested NET, although some features were atypical.…”

“…Our case shows that pancreatic hamartoma can be preoperatively diagnosed using EUS–FNAB. Pancreatic hamartoma is a very rare, non‐neoplastic, mass‐forming pancreatic lesion, 1 with only 64 cases reported in the English literature and 7 in the Japanese literature, without abstract only (based on literature searches using the PubMed and Japanese Ichushi databases) 1–51 . As pancreatic hamartoma is typically asymptomatic, in more than half the abovementioned reports, the cases has been incidentally discovered 1–51 .…”