Repopulation of autophagy-deficient stromal cells with autophagy-intact cells after repeated breeding in uterine mesenchyme-specific Atg7 knockout mice
Abstract:Objective: Autophagy is highly active in ovariectomized mice experiencing hormone deprivation, especially in the uterine mesenchyme. Autophagy is responsible for the turnover of vasoactive factors in the uterus, which was demonstrated in anti-Müllerian hormone receptor type 2 receptor (<i>Amhr2</i>)-Cre-driven autophagy-related gene 7 (<i>Atg7</i>) knockout (<i>Amhr-Cre/Atg7<sup>f/f</sup></i> mice). In that study, we uncovered a striking difference in the amount … Show more
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