Reply to the letter to the editor on “No modulatory effects by tSMS when delivered during a cognitive task”

Kufner, M.; Brückner, Sabrina; Kammer, Thomas

doi:10.1016/j.brs.2017.04.122

Cited by 2 publications

(2 citation statements)

References 9 publications

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“…Towards this end, tSMS has been applied to the motor cortex while participants performed an acoustic oddball task (Kufner, Bruckner, & Kammer, 2017a). No differences were found in post-stimulation MEP in contrast to prior studies that stimulated participants in the resting-state, revealing potential negation of tSMS effects by cognitive tasks (Foffani & Dileone, 2017; Kufner, Bruckner, & Kammer, 2017b). Further studies should include multiple cognitive tasks to investigate this effect and find a task which decreases variability without negating the effects of stimulation.…”

Section: Discussioncontrasting

confidence: 86%

Modulating neural oscillations by transcranial static magnetic field stimulation of the dorsolateral prefrontal cortex: A crossover, double‐blind, sham‐controlled pilot study

Sheffield

Ahn

Alagapan

et al. 2018

Eur J of Neuroscience

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Transcranial static magnetic field stimulation (tSMS) is a novel non-invasive brain stimulation technique that has been shown to locally increase alpha power in the parietal and occipital cortex. We investigated if tSMS locally increased alpha power in the left or right prefrontal cortex, as the balance of left/right prefrontal alpha power (frontal alpha asymmetry) has been linked to emotional processing and mood disorders. Therefore, altering frontal alpha asymmetry with tSMS may serve as a novel treatment to psychiatric diseases. We performed a crossover, double-blind, sham-controlled pilot study to assess the effects of prefrontal tSMS on neural oscillations. Twenty-four right-handed healthy participants were recruited and received left dorsolateral prefrontal cortex (DLPFC) tSMS, right DLPFC tSMS, and sham tSMS in a randomized order. Electroencephalography data were collected before (2 minutes eyes-closed, 2 minutes eyes-open), during (10 minutes eyes-open), and after (2 minutes eyes-open) stimulation. In contrast to our hypothesis, neither left nor right tSMS locally increased frontal alpha power. However, alpha power increased in occipital cortex during left DLPFC tSMS. Right DLPFC tSMS increased post-stimulation fronto-parietal theta power, indicating possible relevance to memory and cognition. Left and right DLPFC tSMS increased post-stimulation left hemisphere beta power, indicating possible changes to motor behavior. Left DLPFC tSMS also increased post-stimulation right frontal beta power, demonstrating complex network effects that may be relevant to aggressive behavior. We concluded that DLPFC tSMS modulated the network oscillations in regions distant from the location of stimulation and that tSMS has region specific effects on neural oscillations.

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Section: Discussioncontrasting

confidence: 86%

Modulating neural oscillations by transcranial static magnetic field stimulation of the dorsolateral prefrontal cortex: A crossover, double‐blind, sham‐controlled pilot study

Sheffield

Ahn

Alagapan

et al. 2018

Eur J of Neuroscience

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“…Activation of the motor cortex without motor output might therefore interfere with neuroplastic modulation induced by static magnetic fields. In a reply to the letter [17], we discussed the possible effects of the oddball task on the excitability of the motor cortex and also mentioned its role in controlling subject's attention [21]. However, we opted for a direct experimental comparison as the best way to address this question.…”

Section: Introductionmentioning

confidence: 99%

Ten minutes of transcranial static magnetic field stimulation does not reliably modulate motor cortex excitability

2020

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Recently, modulatory effects of static magnetic field stimulation (tSMS) on excitability of the motor cortex have been reported. In our previous study we failed to replicate these results. It was suggested that the lack of modulatory effects was due to the use of an auditory oddball task in our study. Thus, we aimed to evaluate the role of an oddball task on the effects of tSMS on motor cortex excitability. In a within-subject-design we compared 10 minutes tSMS with and without oddball task. In one of the two sessions subjects had to solve an auditory oddball task during the exposure to the magnet, whereas there was no task during exposure in the other session. Motor cortex excitability was measured before and after tSMS. No modulation was observed in any condition. However, when data were pooled regarding the order of the sessions, a trend for an increase of excitability was observed in the first session compared to the second session. We now can rule out that the auditory oddball task destroys tSMS effects, as postulated. Our results rather suggest that fluctuations in the amplitudes of single pulse motor evoked potentials may possibly mask weak modulatory effects but may also lead to false positive results if the number of subjects in a study is too low. In addition, there might be a habituation effect to the whole procedure, resulting in less variability when subjects underwent the same experiment twice.

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Reply to the letter to the editor on “No modulatory effects by tSMS when delivered during a cognitive task”

Cited by 2 publications

References 9 publications

Modulating neural oscillations by transcranial static magnetic field stimulation of the dorsolateral prefrontal cortex: A crossover, double‐blind, sham‐controlled pilot study

Modulating neural oscillations by transcranial static magnetic field stimulation of the dorsolateral prefrontal cortex: A crossover, double‐blind, sham‐controlled pilot study

Ten minutes of transcranial static magnetic field stimulation does not reliably modulate motor cortex excitability

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