Reply to the Letter to the Editor: “Comparison of the Safety and Efficacy of Yttrium-90 Radioembolization for Nonalcoholic Fatty Liver Disease-Associated and Hepatitis B Virus-Associated Hepatocellular Carcinoma”

Abstract

difference. The ALBI score, representative of overall liver function, also did not differ significantly between the NALFD and the HBV cohort. Propensity score matching is a well-validated method; however, for our purposes, it would have decreased the statistical power without providing additional insights into NAFLD. The primary aim of our study was to investigate whether NAFLD-associated comorbidities alter the safety and efficacy in selective internal radiotherapy. Using a matching method to overcome the chosen differences between NAFLD and HBV infection was not within the scope of this study.