Reply to Peacock and Rafique and to Blot et al

Kamat, Ishan; Ramachandran, Vignesh; Eswaran, Harish; Guffey, Danielle; Musher, Daniel M.

doi:10.1093/cid/ciz952

Cited by 1 publication

(1 citation statement)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A single TM is predicted at 75-95, with an extracellular catalytic domain. ABHD12 is a monoacylglycerol hydrolase [432], but may also regulate lysophosphatidylserine levels [300]. Loss-of-function mutations in ABHD12 are associated with a disorder known as PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataracts) [172].…”

Section: -Acylglycerol Ester Turnovermentioning

confidence: 99%

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes

Alexander

Fabbro

Kelly

et al. 2019

British J Pharmacology

467

431

View full text Add to dashboard Cite

The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (http://www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.14752. Enzymes are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein‐coupled receptors, ion channels, nuclear hormone receptors, catalytic receptors and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2019, and supersedes data presented in the 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

show abstract

Section: -Acylglycerol Ester Turnovermentioning

confidence: 99%