Reply to Genomic profiles of nasopharyngeal carcinoma: The importance of histological subtyping and Epstein‐Barr virus in situ assays

Ali, Siraj M.; Ross, Jeffrey S.; Wang, Kai

doi:10.1002/cncr.31132

Cited by 1 publication

(1 citation statement)

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“…In 2007, Eriksson et al (111) reported that oncolytic adenoviruses Ad5/3-Delta24 and Ad5.pk7-Delta24 can selectively kill breast cancer-initiating CD44+CD24-/low cells, and Cho et al (112) isolated and characterized CSCs in MMTV-Wnt-1 murine breast tumors. It has also been demonstrated that the Epstein-Barr virus is an important human carcinogen (113), particularly in nasopharyngeal carcinoma (114). In addition, Satoru et al (115) demonstrated that the principal oncoprotein of Epstein-Barr virus, latent membrane protein 1, promotes tumor cell invasion and metastasis, as well as EMT, and is involved in the formation of CSCs in nasopharyngeal cancer.…”

Section: Virus and Escc Stem Cellsmentioning

confidence: 99%

Cancer stem cells in esophageal squamous cell cancer (Review)

et al. 2019

Oncol Lett

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Cancer stem cells (CSCs) are hypothesized to govern the origin, progression, drug resistance, recurrence and metastasis of human cancer. CSCs have been identified in nearly all types of human cancer, including esophageal squamous cell cancer (ESCC). Four major methods are typically used to isolate or enrich CSCs, including: i) fluorescence-activated cell sorting or magnetic-activated cell sorting using cell-specific surface markers; ii) stem cell markers, including aldehyde dehydrogenase 1 family member A1; iii) side population cell phenotype markers; and iv) microsphere culture methods. ESCC stem cells have been identified using a number of these methods. An increasing number of stem cell signatures and pathways have been identified, which have assisted in the clarification of molecular mechanisms that regulate the stemness of ESCC stem cells. Certain viruses, such as human papillomavirus and hepatitis B virus, are also considered to be important in the formation of CSCs, and there is a crosstalk between stemness and viruses-associated genes/pathways, which may suggest a potential therapeutic strategy for the eradication of CSCs. In the present review, findings are summarized along these lines of inquiry.

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Section: Virus and Escc Stem Cellsmentioning

confidence: 99%

Cancer stem cells in esophageal squamous cell cancer (Review)

et al. 2019

Oncol Lett

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Reply to Genomic profiles of nasopharyngeal carcinoma: The importance of histological subtyping and Epstein‐Barr virus in situ assays

Cited by 1 publication

References 3 publications

Cancer stem cells in esophageal squamous cell cancer (Review)

Cancer stem cells in esophageal squamous cell cancer (Review)

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