Reply to editorial and commentaries on Steele, Al-Mufti, Augustyn, Chandrajith, Coghlan, Coulson et al. (2018) "Cause of Cambrian explosion - Terrestrial or Cosmic?"

Steele, Edward J.; Al-Mufti, S.; Augustyn, Kenneth A.; Chandrajith, Rohana; Coghlan, John P.; Coulson, S. G.; Ghosh, Sudipto; Gillman, M. A.; Gorczynski, Reginald M.; Klyce, Brig; Louis, G.; Mahanama, Kithsiri; Oliver, Keith R.; Padron, Julio; Qu, Jiangwen; Schuster, John A.; Smith, William E.; Snyder, Duane P.; Steele, Julian A.; Stewart, Brent J.; Temple, Robert; Tokoro, Gensuke; Tout, Christopher A.; Unzicker, Alexander; Wainwright, Milton; Wallis, Jamie; Wallis, Daryl H.; Wallis, M. K.; Wetherall, J. D.; Wickramasinghe, D. T.; Wickramasinghe, J. T.; Wickramasinghe, N. C.; Liu, Yongsheng

doi:10.1016/j.pbiomolbio.2018.03.007

Cited by 6 publications

(3 citation statements)

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“…The intercellular communications are probably as old as life itself, whichever are the life origins terrestrial, from Haldane-Oparin primordial soup [26; 27], or Panspermic from comets carrying fragments of DNA or viruses or even seeds and fertilised ova [28]. Life on Earth appeared about 3.8 4.2 billion years ago [29] with the oldest forms being filamentous microorganisms in seafloor-hydrothermal ventrelated precipitates, from the Nuvvuagittuq belt in Quebec, Canada.…”

Section: Evolution Of Chemical Transmission Between Cellsmentioning

confidence: 99%

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Early evolutionary history (from bacteria to hemichordata) of the omnipresent purinergic signalling: A tribute to Geoff Burnstock inquisitive mind

Verkhratsky

2021

Biochemical Pharmacology

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Purines and pyrimidines are indispensable molecules of life; they are fundamental for genetic code and bioenergetics. From the very early life forms purines have acquired the meaning of damage-associated extracellular signaller and purinergic receptors emerged in unicellular organisms. Ancestral purinoceptors are P2X-like ionotropic ligand-gated cationic channels ionotropic P2X receptors showing 20 40% of homology with vertebrate P2X receptors; genes encoding ancestral P2X receptors have been detected in Protozoa, Algae, fungi and sponges; they are also present in some invertebrates, but are absent from the genome of insects, nematodes, and higher plants. Plants nevertheless evolved a sophisticated and widespread purinergic signalling system relying on the idiosyncratic purinoceptor P2K1/DORN1 linked to intracellular Ca 2+ signalling. The advance of metabotropic purinoceptors starts later in evolution with adenosine receptors preceding the emergence of P2Y nucleotide and P0 adenine receptors. In vertebrates and mammals the purinergic signalling system reaches the summit and operates throughout all tissues and systems without anatomical or functional segregation.

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Section: Evolution Of Chemical Transmission Between Cellsmentioning

confidence: 99%

“…These are the most resilient animals, which can even survive the unprotected raid on the outer skin of the cosmic satellite orbiting at ~250 km above Earth for 10 days [131]. There are some conjectures (which are perceived by many as a fantasy) about extraterrestrial origin of these remarkable species [28].…”

Section: Tardigradesmentioning

confidence: 99%

Early evolutionary history (from bacteria to hemichordata) of the omnipresent purinergic signalling: A tribute to Geoff Burnstock inquisitive mind

Verkhratsky

2021

Biochemical Pharmacology

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“…There are arguments against it because radiation from space over long distances would not allow traveling of living entities like life on earth. The pansperm theory still has many followers today . There are meteorites which contain up to 90 amino acids, even though we have only 20 as the basis of life on Earth.…”

Section: Are Viruses Alive? Can They Be the Origin Of Life? Will Theymentioning

confidence: 99%

Viruses More Friends than Foes

Moelling

2019

Electroanalysis

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Viruses are normally defined as pathogens and have a bad reputation because of pandemics such as Influenza, HIV/AIDS, Ebola, and SARS. Most viruses are, however, not enemies or killers but play important roles in the origin, development and maintenance of life of all species on our planet. This is new information we learnt by new technologies such as sequencing. Viruses are the most successful species on Earth, they are ubiquitous, in the oceans, in our environment, in animals, plants, bacteria, up in the air, perhaps even in the universe, within our body and even as part of our genomes. They influence our health, our well‐being, mental properties, our gut microbiota including obesity, and may help to cope with multi‐drug‐resistant bacteria. There the phages, viruses of bacteria, raise hopes. Viruses built our immunity: viruses protect against viruses. We do not have to lay eggs – thanks to viruses! They are the drivers of evolution and adaptation to environmental changes, also e. g. in plankton. The success story of viruses started about 3.5 billion years ago when life began. Newly discovered giant viruses are almost bacteria in their composition, suggesting that the borderline between dead matter and life is continuous. There are many open questions – how did life begin, is there life on exoplanets, how to find it? Are virus‐like elements, viroids, important for the origin of life? Will viruses eliminate mankind [1]?

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Editorial

Denis

2018

Progress in Biophysics and Molecular Biology

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Reply to editorial and commentaries on Steele, Al-Mufti, Augustyn, Chandrajith, Coghlan, Coulson et al. (2018) "Cause of Cambrian explosion - Terrestrial or Cosmic?"

Cited by 6 publications

References 0 publications

Early evolutionary history (from bacteria to hemichordata) of the omnipresent purinergic signalling: A tribute to Geoff Burnstock inquisitive mind

Early evolutionary history (from bacteria to hemichordata) of the omnipresent purinergic signalling: A tribute to Geoff Burnstock inquisitive mind

Viruses More Friends than Foes

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