Reply to ‘Comment on ‘The effectiveness and safety of topical beta‐receptor blocker in treating superficial infantile haemangiomas: A meta‐analysis including 20 studies’ Dr. Sun et al.’

Lin, Zhenying

doi:10.1111/bcp.15246

Cited by 1 publication

(1 citation statement)

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“…The latter contains collagen and reticular fibres surrounded by interstitial fibroblasts [29]. The mixed type may consist of elements of capillary or cavernous tumours, but has subcutaneous and external parts and includes other tissues besides the vascular component.…”

Section: Figure 1 Microscopic Picture Of Capillary Vascular Hyperplas...mentioning

confidence: 99%

Clinical and morphological characteristics and diagnosis of external haemangiomas in children

Toktosunova,

Toktosunov,

Sharshenov

2023

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Background. The relevance lies in the increasing occurrence of haemangiomas in children under 1 year old when diagnosis confirmation through morphological methods is necessary. The purpose of the research is to characterise the histological initial and final changes of cutaneous haemangiomas and to present the main clinical manifestations of haemangiomas in children. Materials and methods. Several clinical (for detailed diagnosis of the disease), morphological (histological examination of the material) and statistical methods were used in the work. The object of the research was 98 children with haemangiomas of the facial skin aged 6 months to 16 years. Results. The morphological study demonstrated that in 49 cases (50 %), the typical simple capillary structure of haemangioma was identified, in 35 cases (35.7 %) — cavernous type of neoplasm. Only 18.3 % of the children had combined haemangiomas. Capillary-type haemangiomas contain many small capillaries with a narrow lumen, covered by adhering fleshy epithelium. Conclusions. During the phase of the active growth of haemangiomas, there is a predominance of massive endothelial cells, suggesting that the vascular component, particularly proliferating epithelium-lined capillaries, makes up the main and largest part of the hyperplasia.

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Section: Figure 1 Microscopic Picture Of Capillary Vascular Hyperplas...mentioning

confidence: 99%

Clinical and morphological characteristics and diagnosis of external haemangiomas in children

Toktosunova,

Toktosunov,

Sharshenov

2023

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Reply to ‘Comment on ‘The effectiveness and safety of topical beta‐receptor blocker in treating superficial infantile haemangiomas: A meta‐analysis including 20 studies’ Dr. Sun et al.’

Abstract: We thank Dr. Sun et al. 1 for their comments on our manuscript titled 'The effectiveness and safety of topical beta-receptor blocker in treating superficial infantile haemangiomas: A meta-analysis including 20 studies' 2 and respond to these comments as follows.

Cited by 1 publication

References 8 publications

Clinical and morphological characteristics and diagnosis of external haemangiomas in children

Clinical and morphological characteristics and diagnosis of external haemangiomas in children

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