Reply

Benzoyl Peroxide: A history of early research and researchers

“…The discovery process spanned the years 1901–65 resulting in the identification of benzoyl peroxide as an efficacious drug in the treatment of acne. While Gruber 5 Fishman 4 Frank 6,7 Pace 2 and Petrou 7 can be considered the “fathers” of the modern use of benzoyl peroxide in the treatment of acne, the status of “grandfather” can be bestowed on Kastle 8 Loevenhart 8,9 Lyons and Reynolds 10 and Peck and Chagrin 11 .…”

“…Cunliffe 1 in reviewing the historical background on the use of benzoyl peroxide as an efficacious treatment for acne attributed the discovery to Pace in 1965 2 . Subsequently, issues were raised concerning the historical sequence of events that surrounded the developmental process during the years 1958 through 1965 3–7 . However, there is an earlier history covering the years 1901–34 8–11 .…”