Abstract:We have recently shown that the repression of early transcription during a Simian Virus 40 (SV40) infection results in different histone modifications depending upon the replicative status of the chromatin (Kallestad, et al., 2013, Frontiers in Genetics). In order to test whether replication affected other aspects of transcriptional regulation, we have analyzed SV40 chromosomes for the presence of the methylated forms of H3K4 and H3K9 following dysregulation of transcription by DRB which inhibits RNA Polymeras… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.