Replantation of Uterus and Ovaries in Dogs, With Successful Pregnancy

Eraslan, Şadan

doi:10.1001/archsurg.1966.01320190011002

Cited by 86 publications

(41 citation statements)

References 3 publications

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“…Successful pregnancies in sheep following autotransplantation of the internal genitalia by using revascularization by omentopexy [11] and in dogs by vascular anastomotic techniques [3] have been reported. Homo transplantation of the uterus and ovaries in dogs by vascular anastomosis is accompanied by a high mortality rate.…”

mentioning

confidence: 99%

Uterine Transplantation in Dogs

Scott

Anderson

Kling

et al. 1970

Gynecol Obstet Invest

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An experimental surgical procedure of uterine transplantation using the omentum as a vascular supply was performed in 20 dogs. Eight of the 10 uterine autografts were considered viable. Five of the 10 dogs with homografts were treated with immunosuppressive drugs, but no significant differences in the rejection reaction between the 2 groups were noted. The described clinical behavior, laboratory studies, and gross and microscopic findings supply more information about the rejection characteristics of this organ.

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mentioning

confidence: 99%

Uterine Transplantation in Dogs

Scott

Anderson

Kling

et al. 1970

Gynecol Obstet Invest

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“…To solve this problem, a number of genital transplantation studies and experiments have been performed by vascu lar and nonvascular grafting techniques. In 1966, Eraslan et al [1], observed pregnancies following vascular ized autotransplantation of the uterus, tubes and ovaries in dogs. These authors utilized the hypogastric artery and common iliac veins for vascular reanastomosis to these organs [1,2].…”

Section: Discussionmentioning

confidence: 99%

“…In 1966, Eraslan et al [1], observed pregnancies following vascular ized autotransplantation of the uterus, tubes and ovaries in dogs. These authors utilized the hypogastric artery and common iliac veins for vascular reanastomosis to these organs [1,2]. Winston et al [3] also achieved preg nancies following vascularized autotransplants of ad nexa.…”

Section: Discussionmentioning

confidence: 99%

Microsurgical Transposition of the Human Fallopian Tube

Pabuçcu

Ülgenalp²,

Başer³

et al. 1991

Gynecol Obstet Invest

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“…1 In 2010 Diaz-Garcia and coworkers, at the University of Gothenburg in Sweden, did the world's first successful allogenic uterus transplantation, in a rat, with healthy offspring.…”

Section: Trials On Animalsmentioning

confidence: 99%

Uterine Transplantation: An Option beyond Surrogacy

Srivastava¹,

Patil²,

Shah³

2016

MGM Journal of Medical Sciences

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Over the years, a lot has developed in the field of infertility and artificial reproductive techniques worldwide, but the uterine factor infertility still remains an unresolved issue in reproductive medicine. Absolute uterine factor infertility is synonymous with congenital absence of uterus or a physiologically nonfunctioning uterus. Very few options including surrogacy and adoption are available for these patients. Both surrogacy and adoption are associated with legal, ethical, financial, religious, and psychological issues. For some of these patients, uterine transplant could be a viable option in future. However, the ability of uterus to carry the pregnancy to the period of viability and the effect of immunosuppressant on the fetus make the uterine transplant a more complex operation than any other transplants. From the earliest uterine transplant tried in 1931 in Germany to the first successful child birth following transplant in Sweden in 2014, uterine transplantation has come a long way. Among the countries that have tried this till now, Sweden has reported five cases of successful births posttransplant. Behind these successful cases, there is dedication and perseverance of few individuals who continued their efforts in spite of repeated failures. At the moment, the uterine transplant can be considered experimental at the best. However, considering the large number of hysterectomies done all over the world and uteruses available for transplantation, uterine transplant has potential to surpass, in numbers, the other transplant in near future.

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Replantation of Uterus and Ovaries in Dogs, With Successful Pregnancy

Cited by 86 publications

References 3 publications

Uterine Transplantation in Dogs

Uterine Transplantation in Dogs

Microsurgical Transposition of the Human Fallopian Tube

Uterine Transplantation: An Option beyond Surrogacy

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