Repetitive transcranial magnetic stimulation (rTMS) as a tool for cognitive enhancement in healthy adults: a review study

Asgarinejad, Mostafa; Saviz, Marzieh; Sadjadi, Seyyed Mostafa; Saliminia, Sarah; Kakaei, Amineh; Esmaeili, Peyman; Hammoud, Ahmad; Ebrahimzadeh, Elias; Soltanian-Zadeh, Hamid

doi:10.1007/s11517-023-02968-y

Cited by 3 publications

(1 citation statement)

References 86 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Primarily, the DLPFC, a cortical area unique to primates that evolved to play a central role in cognitive processes, is extensively connected with other brain regions. 24 Previous rTMS research, including studies on cognitive dysfunction, 25 depression, 26 substance, 27 and alcohol dependence, 28 frequently targets the DLPFC. High‐frequency 10‐Hz stimulation has been found to be well‐tolerated by patients in clinical practice and effective in reducing BZD use.…”

Section: Discussionmentioning

confidence: 99%

Effective alleviation of depressive and anxious symptoms and sleep disorders in benzodiazepine‐dependent patients through repetitive transcranial magnetic stimulation

Chen,

Zhang

et al. 2024

Addiction Biology

View full text Add to dashboard Cite

Benzodiazepine (BZD) dependence poses a significant challenge in mental health, prompting the exploration of treatments like repetitive transcranial magnetic stimulation (rTMS). This research aims to assess the impact of rTMS on alleviating symptoms of BZD dependence. A randomized control trial was employed to study 40 BZD‐dependent inpatients. Their symptoms were quantified using the Hamilton Anxiety Rating Scale (HAMA), Montgomery–Åsberg Depression Rating Scale (MADRS) and Pittsburgh Sleep Quality Index (PSQI). Participants were divided into a conventional treatment group (daily diazepam with gradual tapering) with supportive psychotherapy and another group receiving the same treatment supplemented with rTMS (five weekly sessions for 2 weeks). Significant improvements were observed in both groups over baseline in MADRS, HAMA and PSQI scores at the 2nd, 4th, 8th and 12th week assessments (p < 0.05). The group receiving rTMS in addition to conventional treatment exhibited superior improvements in all measures at the 8th and 12th weeks. The addition of rTMS to conventional treatment methods for BZD dependence significantly betters the recovery in terms of depression, anxiety and sleep quality, highlighting the role of rTMS as an effective adjunct therapy.

show abstract