Repeated sprint in hypoxia as a time-metabolic efficient strategy to improve physical fitness of obese women

Camacho-Cardeñosa, Alba; Camacho-Cardeñosa, Marta; Brazo-Sayavera, Javier; Timón, Rafael; González-Custodio, Adrián; Olcina, Guillermo

doi:10.1007/s00421-020-04344-2

Cited by 15 publications

(25 citation statements)

References 45 publications

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“…The warm-up will be 5 min in the mechanical cycle ergometer label Monark (Monark, Brazil) without load (0 Kp). At each 2-min stage, there will be an increase of 0.25 Kp (approximately 13 W) until voluntary exhaustion [ 27 ]. O 2 consumption will be measured with each breath using the gas analyzer (K4b 2 , COSMED, Italy), calibrated according to the manufacturer’s specifications.…”

Section: Methodsmentioning

confidence: 99%

“…More recent studies [ 25 – 30 ] have shown that this type of intervention can provide good health outcomes and that physical training under normobaric hypoxia is safe and can be performed with different populations. For example, studies developed with overweight and obese women showed that a reduction of fat mass has been reported with a concomitant increase in lean mass [ 26 ] and cardiorespiratory fitness [ 27 ]. These results were better in the groups that performed interval training or sprints in hypoxia than those trained in normoxia after 12 weeks (36 sessions).…”

Section: Introductionmentioning

confidence: 99%

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Effects of moderate-intensity intermittent hypoxic training on health outcomes of patients recovered from COVID-19: the AEROBICOVID study protocol for a randomized controlled trial

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Camacho-Cardeñosa

et al. 2021

Trials

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Background Recent studies point to a lower number and reduced severity of cases in higher altitude cities with decreased oxygen concentration. Specific literature has shown several benefits of physical training, so, in this sense, physical training with hypoxic stimulus appears as an alternative that supports the conventional treatments of the COVID-19 patient’s recovery. Thus, this study’s primary aim is to analyze the effects of moderate-intensity intermittent hypoxic training on health outcomes in COVID-19 recovered patients. Methods A clinical trial controlled double-blind study was designed. Participants (30–69 years old) will be recruited among those with moderate to severe COVID-19 symptoms, approximately 30 days after recovery. They will be included in groups according to the training (T) and recovery (R) association with hypoxia (H) or normoxia (N): (a) TH:RH, (b) TN:RH, (c) TN:RN, and last (d) the control group. The 8-week exercise bike intervention will be carried out with a gradual load increase according to the established periods, three times a week in sets of 5 min, 90 to 100% of the anaerobic threshold (AT), and a 2.5-min break. Blood will be collected for genotyping. First, after 4 weeks (partial), after 8 weeks, and later, 4 weeks after the end of the physical training intervention, participants will perform assessments. The primary outcome is the maximum oxygen consumption (VO2peak). The secondary outcomes include lung function, inflammatory mediators, hematological, autonomic parameters, AT, body composition analysis, quality of life, mental health, anthropometric measurements, and physical fitness. The statistical analysis will be executed using the linear regression model with mixed effects at a 5% significance level. Discussion This study is designed to provide evidence to support the clinical benefits of moderate-intensity intermittent hypoxic training as a part of the treatment of patients recovered from COVID-19. It may also provide evidence on the efficacy and safety of intermittent hypoxic training in different health conditions. Lastly, this study presents an innovative strategy enabling up to 16 participants in the same training session. Trial registration ClinicalTrials.gov RBR-5d7hkv. Registered after the start of inclusion on 3 November 2020 with the Brazilian Clinical Trials Registry

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effects of moderate-intensity intermittent hypoxic training on health outcomes of patients recovered from COVID-19: the AEROBICOVID study protocol for a randomized controlled trial

Trapé

Camacho-Cardeñosa

et al. 2021

Trials

Self Cite

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“…The warm-up will be 5 minutes in cycle ergometer (E200, COSMED, Italy) without load (0 Kp). At each 2-minute stage, there will be an increase of 0.25 Kp (approximately 13 W) until voluntary exhaustion [27]. O 2 consumption will be measured with each breath, using the gas analyser (K4b 2 , COSMED, Italy), which will be calibrated according to the manufacturer's speci cations.…”

Section: In Ammatory Lipid Mediatorsmentioning

confidence: 99%

“…More recent studies have shown that this type of intervention can present good health outcomes and that physical training under normobaric hypoxia is safe and can be performed with different populations. A reduction of fat mass has been reported with a concomitant increase in lean mass [26] and increases in cardiorespiratory tness [27] in overweight and obese women. These results were better in the groups that performed interval training or sprints in hypoxia than those trained in normoxia after 12 weeks (36 sessions).…”

Section: Introductionmentioning

confidence: 99%

“…Although the studies previously mentioned [26][27][28][29] had shown health bene ts for participants right after the intervention, a recent study [31] that performed high-intensity training under hypoxic conditions found effects after four weeks of the end of the intervention. At that moment, the trunk fat mass of overweight and obese women decreased signi cantly compared with the result after the intervention.…”

Section: Introductionmentioning

confidence: 99%

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Effects of moderate-intensity intermittent hypoxic training on health outcomes of patients recovered from covid-19: the AEROBICOVID study protocol for a randomised controlled trial

Trapé

Camacho-Cardeñosa

Merellano-Navarro

et al. 2021

Preprint

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Background: Recent studies point to a lower number and a reduction in the severity of cases in higher altitude cities, with decreased oxygen concentration. Specific literature has shown several benefits of physical training, so, in this sense, physical training with hypoxic stimulus appears as an alternative that supports the conventional treatments of the COVID-19 patient's recovery. Thus, this study's primary aim is to analyse the effects of moderate-intensity intermittent hypoxic training on health outcomes in COVID-19 recovered patients. Methods: A clinical trial controlled double-blind study was designed. Participants (30-69 years old) will be recruited among those with moderate to severe COVID-19 symptoms, approximately 30 days after recovery. They will be included in groups according to the training (T) and recovery (R) association with hypoxia (H) or normoxia (N): a) TH:RH, b) TN:RH, c) TN:RN, and, last, d) the control group. The 8-week exercise bike intervention will be carried out with a gradual load increase according to the established periods, three times a week in sets of 5 minutes, 90 to 100% of the anaerobic threshold (AT), and a 2,5-minute break. Blood will be collected for genotyping. First, after four weeks (partial), after eight weeks, and later, four weeks after the end of the physical training intervention, participants will perform assessments. The primary outcome is the maximum oxygen consumption (VO2max). The secondary outcomes include lung function, inflammatory mediators, haematological, autonomic parameters, AT, body composition analysis, quality of life, mental health, anthropometric measurements, and physical fitness. The statistical analysis will be executed using the linear regression model with mixed effects at a 5% significance level. Discussion: This study is designed to provide evidence to support the clinical benefits of moderate-intensity intermittent hypoxic training as a part of the treatment of patients recovered from COVID-19. It may also provide evidence on the efficacy and safety of intermittent hypoxic training in different health conditions. Lastly, this study presents an innovative strategy enabling up to 16 participants in the same training session.Trial registration: Brazilian Clinical Trials Registry, RBR-5d7hkv. Registered after the start of inclusion; 3 November 2020; https://ensaiosclinicos.gov.br/rg/RBR-5d7hkv

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Recommendations for Women in Mountain Sports and Hypoxia Training/Conditioning

Burtscher,

Raberin,

Brocherie

et al. 2023

Sports Med

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The (patho-)physiological responses to hypoxia are highly heterogeneous between individuals. In this review, we focused on the roles of sex differences, which emerge as important factors in the regulation of the body’s reaction to hypoxia. Several aspects should be considered for future research on hypoxia-related sex differences, particularly altitude training and clinical applications of hypoxia, as these will affect the selection of the optimal dose regarding safety and efficiency. There are several implications, but there are no practical recommendations if/how women should behave differently from men to optimise the benefits or minimise the risks of these hypoxia-related practices. Here, we evaluate the scarce scientific evidence of distinct (patho)physiological responses and adaptations to high altitude/hypoxia, biomechanical/anatomical differences in uphill/downhill locomotion, which is highly relevant for exercising in mountainous environments, and potentially differential effects of altitude training in women. Based on these factors, we derive sex-specific recommendations for mountain sports and intermittent hypoxia conditioning: (1) Although higher vulnerabilities of women to acute mountain sickness have not been unambiguously shown, sex-dependent physiological reactions to hypoxia may contribute to an increased acute mountain sickness vulnerability in some women. Adequate acclimatisation, slow ascent speed and/or preventive medication (e.g. acetazolamide) are solutions. (2) Targeted training of the respiratory musculature could be a valuable preparation for altitude training in women. (3) Sex hormones influence hypoxia responses and hormonal-cycle and/or menstrual-cycle phases therefore may be factors in acclimatisation to altitude and efficiency of altitude training. As many of the recommendations or observations of the present work remain partly speculative, we join previous calls for further quality research on female athletes in sports to be extended to the field of altitude and hypoxia.

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Repeated sprint in hypoxia as a time-metabolic efficient strategy to improve physical fitness of obese women

Cited by 15 publications

References 45 publications

Effects of moderate-intensity intermittent hypoxic training on health outcomes of patients recovered from COVID-19: the AEROBICOVID study protocol for a randomized controlled trial

Effects of moderate-intensity intermittent hypoxic training on health outcomes of patients recovered from COVID-19: the AEROBICOVID study protocol for a randomized controlled trial

Effects of moderate-intensity intermittent hypoxic training on health outcomes of patients recovered from covid-19: the AEROBICOVID study protocol for a randomised controlled trial

Recommendations for Women in Mountain Sports and Hypoxia Training/Conditioning

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