Repeated Heart Rate Measurement and Cardiovascular Outcomes in Left Ventricular Systolic Dysfunction

Hamill, Victoria; Ford, Ian; Fox, Kim; Böhm, Michael; Borer, Jeffrey S.; Ferrari, Roberto; Komajda, Michel; Steg, Philippe Gabriel; Tavazzi, Luigi; Tendera, Michał; Swedberg, Karl

doi:10.1016/j.amjmed.2015.04.042

Cited by 25 publications

(19 citation statements)

References 16 publications

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“…The changes in the CV system are complex, and some of them could have a negative influence, such as maladaptation to chronic volume overload and impaired myocardial relaxation, alteration of left ventricular (LV) contractility and function, and decrease of the carotid artery elasticity . Pregnancy entails an important stress to the heart, with an increase in the heart rate, ventricular volumes, cardiac output, and ventricular hypertrophy; and some of these factors, such as heart rate or ventricular hypertrophy, have been related to poor prognosis in HF patients. However, in our view, beneficial pregnancy‐related changes are more frequent and more relevant; these include the decline in vascular resistance, related, in part, to the increase of atrial natriuretic peptide and relaxin .…”

Section: Discussionmentioning

confidence: 99%

Influence of sex and pregnancy on survival in patients admitted with heart failure: Data from a prospective multicenter registry

Martínez‐Sellés

Díez‐Villanueva

García

et al. 2018

Clinical Cardiology

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Section: Discussionmentioning

confidence: 99%

Influence of sex and pregnancy on survival in patients admitted with heart failure: Data from a prospective multicenter registry

Martínez‐Sellés

Díez‐Villanueva

García

et al. 2018

Clinical Cardiology

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“…It predicts longevity and current evidence suggests that it is also an important marker in cardiovascular diseases, including heart failure [7]. Moreover, the prognostic value of repeated RHR measurements has been strongly related to cardiovascular outcomes more than a single baseline RHR [8]. Margin requirements for the other pages Paper size this page US Letter Some limitations of this study include the fact that only a limited number of male subjects of young age were tested.…”

Section: Discussionmentioning

confidence: 99%

Beat-to-beat heart rate detection by smartphone's accelerometers: Validation with ECG

Landreani

Martín-Yebra

Casellato

et al. 2016

2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

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Abstract-Mobile phones offer the possibility to monitor and track health parameters. Our aim was to test the feasibility and accuracy of measuring beat-to-beat heart rate using smartphone accelerometers by recording the vibrations generated by the heart during its function and transmitted to the chest wall, i.e. the so-called seismocardiographic signal (SCG). Methods: 9 healthy male volunteers were studied in supine (SUP) and in standing (ST) posture. A smartphone (iPhone6, Apple) was positioned on the thorax (POS1) to acquire SCG signal. While supine, a second smartphone was positioned on the navel (POS2). The SCG signal was recorded for 3 minutes during spontaneous respiration, synchronous with 3-leads ECG. Using a fully automated algorithm based on amplitude thresholding after rectification, the characteristic peak of the SCG signal (IVC) was detected and used to compute beat-to-beat heart duration, to be compared with the corresponding RR intervals extracted from the ECG. Results: A 100% feasibility of the approach resulted for POS1 in SUP, while 89% in POS2, and 78% for POS1 in ST. In supine, for each smartphones' position, the automated algorithm correctly identified the cardiac beats with >98% accuracy. Linear correlation (r²) with RR was very high (>0.98) in each posture and position, with no bias and narrow limits of agreement. Conclusions: The obtained results proved the feasibility of the proposed approach and the robustness of the applied algorithm in measuring the beat-to-beat heart rate from smartphonederived SCG, with high accuracy compared to conventional ECG-derived measure.

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“…For example, heart rate obtained from RHM has yet to be studied. A post hoc analysis of the Ivabradine and Outcomes in Chronic Heart Failure trial36 found that time-updated heart rate improved risk stratification for adverse cardiovascular events compared with baseline heart rate alone 37. Additionally, novel waveform analytical methods of aortic pressure tracings quantifying ventricular-vascular coupling38 39 may identify actionable changes in cardiovascular dynamics that precede a rise in filling pressures.…”

Section: Additional Considerationsmentioning

confidence: 99%

Chronic heart failure management and remote haemodynamic monitoring

Wolfson

Fong

Grazette

et al. 2018

Heart

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Heart failure (HF) has a large societal and economic burden and is expected to increase in magnitude and complexity over the ensuing years. A number of telemonitoring strategies exploring remote monitoring and management of clinical signs and symptoms of congestion in HF have had equivocal results. Early studies of remote haemodynamic monitoring showed promise, but issues with device integrity and implantation-associated adverse events hindered progress. Nonetheless, these early studies established that haemodynamic congestion precedes clinical congestion by several weeks and that remote monitoring of intracardiac pressures may be a viable and practical management strategy. Recently, the safety and efficacy of remote pulmonary artery pressure-guided HF management was established in a prospective, single-blind trial where randomisation to active pressure-guided HF management reduced future HF hospitalisations. Subsequent commercial use studies reinforced the utility of this technology and post hoc analyses suggest that tight haemodynamic management of patients with HF may be an additional pillar of therapy alongside established guideline-directed medical and device therapy. Currently, there is active exploration into utilisation of this technology and management paradigm for the timing of implantation of durable left ventricular assist devices (LVAD) and even optimisation of LVAD therapy. Several ongoing clinical trials will help clarify the extent and utility of this strategy along the spectrum of patient with HF from individuals with chronic, stable HF to those with more advanced disease requiring heart replacement therapy.

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Repeated Heart Rate Measurement and Cardiovascular Outcomes in Left Ventricular Systolic Dysfunction

Cited by 25 publications

References 16 publications

Influence of sex and pregnancy on survival in patients admitted with heart failure: Data from a prospective multicenter registry

Influence of sex and pregnancy on survival in patients admitted with heart failure: Data from a prospective multicenter registry

Beat-to-beat heart rate detection by smartphone's accelerometers: Validation with ECG

Chronic heart failure management and remote haemodynamic monitoring

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