Repeatability of intraoperative central corneal and residual stromal thickness measurement using a handheld ultrasound pachymeter

Reinstein, Dan Z.; Archer, Timothy J; Gobbé, Marine

doi:10.1016/j.jcrs.2011.08.037

Cited by 9 publications

(3 citation statements)

References 37 publications

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“…This could be due to the fact that our sample was more homogeneous considering the ages of the subjects and, as such, less prone to variations. With the exception of the DGH-500, the within-subject repeatability of CCT measurements found in the present study in both sessions (3.7 μm and 3.4 μm for the Artemis-2; 5.1 μm and 5.0 μm for the SP- 3000P) was within the range of 3–5 μm repeatability reported for CCT measurements obtained in a standard clinical setting with the patient in a sitting position 32. This suggests that within-subject repeatability was best with the Artemis-2 and worst with the DGH-500.…”

Section: Discussionsupporting

confidence: 82%

Repeatability and interobserver reproducibility of Artemis-2 high-frequency ultrasound in determination of human corneal thickness

Ogbuehi¹,

Osuagwu²

2012

OPTH

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BackgroundThe purpose of this study was to assess the repeatability and limits of agreement of corneal thickness values measured by a high-frequency ultrasound (Artemis-2), hand-held ultrasound pachymeter (DGH-500) and a specular microscope (SP-3000P).MethodsCentral corneal thickness (CCT) was analyzed in this prospective randomized study that included 32 patients (18 men and 14 women) aged 21–24 years. Measurements were obtained in two sessions, one week apart, by two examiners with three devices in a randomized order. Nine measurements were taken (three with each device) on one randomly selected eye of each patient in each measurement session. The coefficient of repeatability and interobserver reproducibility for the values of each method were calculated. The limits of agreement between techniques were also evaluated.ResultsThere were no significant differences in CCT values between sessions for each of the three devices (P > 0.05). The repeatability coefficients for the Artemis-2 (±8 μm/±9 μm) were superior to those of the SP-3000P (±9 μm/±11 μm) and DGH 500 (±12 μm/±12 μm) in session 1/session 2 respectively, while the interobserver reproducibility index (differences between session 1 and session 2) was superior for the SP-3000P (±17 μm) with respect to DHG-500 (±29 μm) and the Artemis-2 (±31 μm). In session 1 and session 2, the limits of agreement between the techniques were 35 μm to −31 μm and 34 to −20 μm, respectively, for DGH-500 versus Artemis-2, 73 μm to 3 μm and 60 μm to 9 μm for Artemis-2 versus SP-3000P, and 58 μm to 22 μm and 72 μm to 10 μm for DGH-500 versus SP-3000P comparisons. The DGH-500 and Artemis-2 gave similar values (P > 0.05) in both sessions, but both (Artemis-2 and DGH-500) values were significantly greater than that of the SP-3000P (P < 0.05) in both sessions.ConclusionRepeatability was comparably good for the three techniques. However, interobserver reproducibility was approximately twice as good with the SP-3000P compared with the other two devices. The Artemis-2 CCT values consistently agreed with the DGH-500 and less so with the SP-3000P. The Artemis-2 provided CCT values that were, on average, 38 μm and 34 μm greater than that of the SP-3000P in session 1 and session 2, respectively.

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Section: Discussionsupporting

confidence: 82%

Repeatability and interobserver reproducibility of Artemis-2 high-frequency ultrasound in determination of human corneal thickness

Ogbuehi¹,

Osuagwu²

2012

OPTH

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“…Before USP measurements, topical anesthesia must be instilled and this could induce bias in the measurements. Moreover, this instrument is a contact type pachymeter, requiring aseptic precautions and anesthetizing the cornea, and the further possibility of injury to the cornea [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Accuracy of optical coherence tomography (OCT) in pachymetry for glaucoma patients

Ayala

Strandås

2015

BMC Ophthalmol

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BackgroundCentral corneal thickness (CCT) measurement has become an important test in the diagnosis and management of glaucoma. Currently, ultrasound corneal thickness measurement (pachymetry) is the most frequently used clinical technique and the gold standard to assess CCT. Newer instruments are currently available including the optical coherence tomography (OCT) instrument. The aim of the present study was therefore to evaluate the accuracy of the CCT measurements performed by three different observers, both with the OCT and ultrasound pachymetry (USP), in patients suffering from glaucoma.MethodsPatients who had been previously diagnosed with glaucoma participated in this cross-sectional study. Glaucoma was defined as patients who had at least two repeatable Humphrey visual fields showing glaucoma damage using the software 24–2, and with the optic nerve showing typical glaucoma damage. The patients CCTs were measured with OCT and USP by three different examiners.ResultsSeventy eyes of 35 patients were included. The average age was 74 ± standard deviation (SD) 10.88, the average pachymetry value with OCT was 536 ± 29 μm, and the average pachymetry with USP was 532 ± 32 μm. The differences between OCT and USP were not significant (t-test, p = 0.32). The intraclass correlation coefficients were, for OCT, 0.99 [confidence interval (CI): 0.98–0.996], and for USP, 0.97 (CI: 0.95–0.98).ConclusionsAgreement among the three observers using OCT or USP for pachymetry measurements was good. OCT might be used as an alternative method for pachymetry in glaucoma patients.

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“…Intraoperative measurement of residual stromal bed thickness using handheld ultrasound may cause potential measurement errors, including inter-user variability, alteration of stromal bed hydration, applicative force, and variation of perpendicular orientation to the cornea. 24 Single site analyses during intraoperative ultrasonic computation may neglect potential areas of even greater attenuation than that which is measured (ie, irregular flap creation). 25 Comparative analysis between these instruments demonstrated higher residual stromal bed thickness values reported by handheld ultrasound and OCT in contrast to VHFDU measurements.…”

Section: Residual Stromal Bed Thicknessmentioning

confidence: 99%

LASIK Enhancement: Clinical and Surgical Management

Moshirfar¹,

Jehangir²,

Fenzl³

et al. 2017

J Refract Surg

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Repeatability of intraoperative central corneal and residual stromal thickness measurement using a handheld ultrasound pachymeter

Abstract: The repeatability of intraoperative handheld US pachymetry was similar between measurements of CCT and measurements of central RST; the CoV was 1.46% in both cases.

Cited by 9 publications

References 37 publications

Repeatability and interobserver reproducibility of Artemis-2 high-frequency ultrasound in determination of human corneal thickness

Repeatability and interobserver reproducibility of Artemis-2 high-frequency ultrasound in determination of human corneal thickness

Accuracy of optical coherence tomography (OCT) in pachymetry for glaucoma patients

LASIK Enhancement: Clinical and Surgical Management

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