Repeatability of Corneal Thickness Measured Using an Oculus Pentacam

Miranda, Marco; Radhakrishnan, Hema; O’Donnell, Clare

doi:10.1097/opx.0b013e318196a737

Cited by 52 publications

(40 citation statements)

References 34 publications

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“…The results of this study indicate that the coefficient of variation (as based on a normalized standard deviation) of Pentacam measures across the cornea can be <1% for central and mid-periphery pachymetry and close to 1% for peripheral near-to-limbus assessments. We found a high repeatability for CCT (mean CV = 0.6%), similar to repeatability indicators previously reported by Khoramnia [19].…”

Section: Discussionsupporting

confidence: 89%

“…While there have been many reports on the use of Pentacam to assess the central cornea [3,[5][6][7][8][9][10], less attention has been given to repeatability of Pentacam pachymetry at the near-to-limbus corneal location [19]. The purpose of this study was to assess the repeatability of such peripheral corneal thickness measurements, using Pentacan pachymetry in healthy eyes.…”

Section: Introductionmentioning

confidence: 99%

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Repeatability of Pentacam peripheral corneal thickness measurements

Martín

Jonuscheit

Rio-Cristobal

et al. 2015

Contact Lens and Anterior Eye

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Section: Discussionsupporting

confidence: 89%

Section: Introductionmentioning

confidence: 99%

Repeatability of Pentacam peripheral corneal thickness measurements

Martín

Jonuscheit

Rio-Cristobal

et al. 2015

Contact Lens and Anterior Eye

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“…New parameters, such as corneal volume, pachymetric progression and elevation maps are of SD= standard deviation; min= minimum; max= maximum; D= diopters; μm= micrometers; mm= millimeters; mmHg= millimeters of mercury; K-Ave= central keratometry; CA= corneal astigmatism ; CCT= central corneal thickness; AC depth= anterior chamber depth; CV= corneal volume; CH= corneal hysteresis; CRF= corneal resistance factor great utility in clinical practice (8)(9)(10)(13)(14)(33)(34)(35)(36) . In the present study, we were able to detect statistical difference in all anterior segment parameters given by the Pentacam rotating Scheimpflug camera.…”

Section: Discussionmentioning

confidence: 99%

“…Logistic regression was used to support the cutoff point identified with the ROC curve analysis. (5)(6)(7)(8)(9)(10)(11)(12)(13)(14) . However, accurate differentiation of keratoconus from healthy corneas is not yet sufficient, as there is a need to detect corneas with a higher susceptibility to becoming ectatic after laser photoablative surgery (15)(16) .…”

Section: Ability Of Corneal Biomechanical Metrics and Anterior Segmenmentioning

confidence: 99%

Ability of corneal biomechanical metrics and anterior segment data in the differentiation of keratoconus and healthy corneas

Fontes¹,

Ambrósio²,

Jardim³

et al. 2010

Arq. Bras. Oftalmol.

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Purpose: To evaluate the sensitivity, specificity, and test accuracy of corneal biomechanical metrics and anterior segment data in differentiating keratoconus from healthy corneas. Methods: Comparative case series. Patients with and without keratoconus (gender and age-matched) were submitted for complete eye examinations including corneal hysteresis (CH) and corneal resistance factor (CRF) as measured by the Ocular Response Analyzer and anterior segment data as gathered through Pentacam assessments. The anterior segment data measurement included average central keratometric readings (K-Ave), corneal astigmatism (CA), central corneal thickness (CCT), anterior chamber depth (AC depth) and corneal volume (CV). All parameters were assessed, compared and analyzed. A receiver operating characteristic (ROC) curve was used to identify the best cutoff point by which to maximize the sensitivity and specificity of discriminating keratoconus from normal corneas for each data category. Results: Seventy seven eyes from forty three patients (24 male, 19 female) with keratoconus and eighty six eyes from forty three (24 male, 19 female) healthy controls were enrolled. ROC curve analysis showed poor overall predictive accuracy for all studied parameters in differentiating keratoconus from normal corneas. The highest sensitivity (79.2%) was obtained for both AC depth and CH (cutoff points 3.22 mm and 9.39 mmHg respectively). The best specificity (89.5%) and test accuracy (80.34%) were obtained for CA (cutoff point of 2.2 D). Conclusion: When considered together, studied parameters showed statistical differences between groups. However, when considered independently they presented low sensitivity, specificity and test accuracy in differentiating keratoconus from healthy corneas. Keywords: Cornea; Corneal diseases; Corneal topography; Biomechanics; Keratoconus. RESUMOObjetivo: Avaliar a sensibilidade, especificidade e acurácia de parâmetros biomecânicos e anatômicos do segmento anterior isolados na diferenciação de córneas saudáveis e com ceratocone. Métodos: Estudo tipo série de casos comparativa. Pacientes com ceratocone e controles saudáveis foram pareados (idade e sexo) e submetidos a exame oftalmológico completo, incluindo avaliação biomecânica (ORA) e tomográfica (Pentacam). Ceratometria central média, astigmatismo corneano, espessura corneana central, profundidade da câmara anterior, volume corneano, CH e CRF foram estabelecidos, avaliados e comparados. Curvas ROC (Receiver operating characteristic) foram utilizadas para identificar o melhor valor de corte que apresentasse a maior sensibilidade e especificidade na discriminação entre ceratocone e córneas saudáveis para cada dado estudado. Resultados: Setenta e sete olhos de 43 pacientes com ceratocone (24 homens e 19 mulheres) e 86 olhos de pacientes saudáveis (24 homens e 19 mulheres) foram incluídos no estudo. Curvas ROC mostraram baixa acurácia na predição do diagnóstico de ceratocone em todos os parâmetros isolados estudados. Maior sensibilidade encontrada foi 79,...

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“…As we moved peripherally, the correlation remained high, albeit not as strong as that in the central area. Similarly, other authors have reported an increase in variability in corneal pachymetry measurements from the center to the periphery, particularly in the superior cornea (4,(14)(15)(16)(17) . They attributed this variability to the effects of the superior eyelid (4) .…”

Section: Discussionmentioning

confidence: 99%

Assessment of anterior and posterior corneal indices using two Scheimpflug analyzers

Fahd¹,

Cherfan²,

Raad³

et al. 2014

Arquivos Brasileiros De Oftalmologia

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Purpose: To assess the agreement between the elevation and curvature measurements of the anterior and posterior corneal surfaces obtained using the Galilei Dual Scheimpflug Analyzer and those obtained using the Pentacam single Scheim pflug system. Methods: This prospective, noninterventional, diagnostic study was conducted at the Department of Ophthalmology at the American University of Beirut (Medical Center) and included 60 eyes of 60 consecutive patients. Measurements were obtained using 2 different Scheimpflug analyzers (Galilei and Pentacam). The best-fit sphere was set at 8 mm in both machines. Pachymetry (CCT), anterior elevation (AE) and posterior elevation (PE), and curvature were assessed. Pearson's correlation coefficients, comparison of means, and Bland-Altman plots were used to evaluate agreement between the 2 systems. Results: The average CCT (at the corneal apex) was 533 ± 35 μm and 532 ± 37 μm (p=0.980), the average central AE was 1.25 ± 3.95 μm and 2.

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Repeatability of Corneal Thickness Measured Using an Oculus Pentacam

Abstract: Our data showed that the Oculus Pentacam provides repeatable measures of corneal thickness when measured within a few seconds, after 1 h, and 1 week.

Cited by 52 publications

References 34 publications

Repeatability of Pentacam peripheral corneal thickness measurements

Repeatability of Pentacam peripheral corneal thickness measurements

Ability of corneal biomechanical metrics and anterior segment data in the differentiation of keratoconus and healthy corneas

Assessment of anterior and posterior corneal indices using two Scheimpflug analyzers

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