Repeatability of a new swept-source optical coherence tomographer and agreement with other three optical biometers

Cheng, Shiming; Zhang, Jiasheng; Xu, Shihong; Wu, Ze-Tong; Li, Tiantian; Lin, Junhai; Yu, A-Yong

doi:10.1007/s00417-022-05579-9

Cited by 25 publications

(39 citation statements)

References 32 publications

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“…Huang et al 11 used OA2000 to measure the biological parameters of normal subjects and compared it with the PCIbased IOLMaster, which proved that OA-2000 had good repeatability and reproducibility for the biological parameters of healthy eyes. Previous studies proved that OA-2000 and IOLMaster show high consistency in most biometric parameters of normal subjects 12,13 . What is the accuracy of biological parameters obtained with the OA-2000 for SO-lled eyes?…”

Section: Introductionmentioning

confidence: 91%

Comparison of ocular biometry obtained with Tomey OA-2000 and IOLMaster 700 in silicone oil-filled eyes

Xiong

Lin

Zhao

et al. 2022

Preprint

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Purpose To evaluate a new non-contact instrument (OA-2000) measuring the ocular biometry parameters of silicone oil (SO)-filled aphakia eyes, as compared with IOLMaster 700. Methods Forty SO-filled aphakia eyes of 40 patients were enrolled in this cross-sectional clinical trial. The axial length (AL), central corneal thickness (CCT), keratometry (Kf [flattest keratometry] and Ks [steep keratometry, 90° apart from Kf]), and axis of the Kf (Ax1) measured with OA-2000 were compared with those measured with IOLMaster 700. The agreements of the results between the two devices were evaluated by Bland-Altman analysis. The differences of measurement results were evaluated by paired t test, and the correlation was evaluated by the Pearson coefficient. Results The mean AL obtained with the OA-2000 was 23.57 ± 0.93mm (range: 21.50 to 25.68mm), and that obtained with the IOLMaster 700 was 23.69 ± 0.94mm (range: 21.85 to 25.86mm), resulting in a mean offset of 0.124 ± 0.125mm (p < 0.001). The AL obtained with the two devices showed a strong linear correlation (r = 0.991). It was also found that the Kf, Ks and Ax1had excellent correlation (Kf, r = 0.980; Ks, r = 0.987; and Ax1, r = 0.966). There was no statistical significance in the pair t test of the Kf, Ks and Ax1. The CCT obtained with the OA-2000 was 530.7 ± 30.9µm (range: 470 to 578µm), and that obtained with the IOLMaster 700 was 545.3 ± 33.9µm (range: 479 to 600µm). The average offset was 14.6 ± 7.5µm, p < 0.001. The coefficient of variations of the biometric parameters obtained with the two devices were lower than 1% except for the Ax1. Conclusion In SO-filled aphakia eyes, the ocular biometry obtained with the OA-2000 and IOLMaster 700 has good correlation and consistency. OA-2000 is an accurate instrument that can provide fundus surgeons with the interesting information on ocular biological parameters of SO-filled aphakia eyes.

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Section: Introductionmentioning

confidence: 91%

Comparison of ocular biometry obtained with Tomey OA-2000 and IOLMaster 700 in silicone oil-filled eyes

Xiong

Lin

Zhao

et al. 2022

Preprint

View full text Add to dashboard Cite

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“…Huang et al 10 used OA2000 to measure the biological parameters of normal subjects and compared it with the PCIbased IOLMaster, which proved that OA-2000 had good repeatability and reproducibility for the biological parameters including AL, anterior chamber depth (ACD), keratometry (K), lens thickness, and corneal diameter values. Previous studies proved that OA-2000 and IOLMaster showed high intra-session consistency in most biometric parameters (including AL [11][12][13] , K 12,13 , ACD 12 ) of normal subjects. Reitblat et.…”

Section: Introductionmentioning

confidence: 94%

Evaluation and comparison of ocular biometric parameters obtained with Tomey OA-2000 in silicone oil-filled aphakia eyes

Xiong

Lin

Zhao

et al. 2022

Preprint

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Purpose To evaluate a new non-contact instrument (OA-2000) measuring the ocular biometry parameters of silicone oil (SO)-filled aphakia eyes, as compared with IOLMaster 700. Methods Forty SO-filled aphakia eyes of 40 patients were enrolled in this cross-sectional clinical trial. The axial length (AL), central corneal thickness (CCT), keratometry (Kf [flattest keratometry] and Ks [steep keratometry, 90° apart from Kf]), and axis of the Kf (Ax1) measured with OA-2000 were compared with those measured with IOLMaster 700. The agreements of the results between the two devices were evaluated by Bland-Altman analysis. The differences of measurement results were evaluated by paired t test, and the correlation was evaluated by the Pearson coefficient. The coefficient of variation (CoV) was calculated to assess the repeatability. Results The mean AL obtained with the OA-2000 was 23.57 ± 0.93mm (range: 21.50 to 25.68mm), and that obtained with the IOLMaster 700 was 23.69 ± 0.94mm (range: 21.85 to 25.86mm), resulting in a mean offset of 0.124 ± 0.125mm (p < 0.001). The mean offset of CCT measured by OA-2000 and IOLMaster 700 was 14.6 ± 7.5µm (p < 0.001). However, the Kf, Ks and Ax1 values from the two devices were comparable (p > 0.05). All the measured parameters of the two devices showed strong linear correlations (all r ≥ 0.966). Bland-Altman analysis showed a narrow 95% limits of agreement (LoA) of Kf, Ks and AL, but 95%LoA of CCT and Ax1 was wide, which were − 29.3 ~ 0.1µm and-25.9 ~ 30.7°respectively. The CoVs of the biometric parameters obtained with OA-2000 were lower than 1%. Conclusion In SO-filled aphakia eyes, the ocular parameters (including AL, Kf, Ks, Ax1, and CCT) measured by the OA-2000 and IOLMaster 700 had a good correlation. Two devices had an excellent agreement on ocular biometric measurements of Kf, Ks and AL. OA-2000 provided excellent repeatability of ocular biometry parameters in SO-filled aphakia eyes.

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“…This within‐subject SD is derived from a one‐way analysis of variance (ANOVA) as the square root of the within‐groups mean square 1 . Repeatability for AL ranged from 4 to 50 μm with a median value of 12 μm; for central corneal thickness (CCT) repeatability it was found to be between 0.7 and 20.3 μm with a median of 2.8 μm; for anterior chamber depth/aqueous depth (ACD/AQD) within‐subject SD ranged from 3 to 134 μm with a median of 20 μm and for keratometry (mean K) repeatability ranged from 0.01 dioptres (D) to 0.21 D with a median of 0.09 D. These investigations studied healthy subjects (from 19 to 91 years old) or those prior to cataract surgery, comprised between 29 and 119 subjects per study 2–27 and included one meta‐analysis 28 . Additionally, we refer to a recent review of ocular biometry using SS‐OCT by Montés‐Micó 29 …”

Section: Introductionmentioning

confidence: 99%

Feasibility and repeatability of ocular biometry measured with IOLMaster 700 in a large population‐based study

Michael

Wirkner

Engel

et al. 2023

Ophthalmic Physiologic Optic

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Purpose To evaluate the feasibility and repeatability of IOLMaster 700 biometry measurements in an adult population. Furthermore, to assess the value of the Quality Indicators (QIs) provided by the device. Method As part of the large population‐based Leipzig Research Centre for Civilization Diseases (LIFE) Adult‐Study, randomly selected participants from Leipzig, Germany were evaluated with the ZEISS IOLMaster 700. Age range was 26–85 years, with 53% of participants above 70 years of age. Axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT) and keratometry (K) were assessed in 1767 right eyes. Measurements were repeated twice and in a subset of 1331 eyes, three times. Measurement feasibility was evaluated for three levels; successful, with warnings and failed, using the inbuilt QIs. Repeatability was assessed as within‐subject standard deviation (SD) and repeatability limits were calculated. Results First measurement success rate for phakic eyes was over 99% for AL, CCT, ACD, over 98% for LT and over 97% for K. K had 16% eyes with warnings and the recommendation to repeat the measurement. Excluding the measurements with warnings resulted in a reduction of mean SD for AL from 48 to 4 μm and for mean K from 0.08 to 0.04 D. Repeatability for phakic eyes was 8 μm for AL, CCT, ACD and LT and 2.3 μm for CCT; 0.07 D and 0.12 D for mean K and delta K, respectively, for phakic cases without warnings (two measurements). Conclusions In our population‐based sample, the IOLMaster 700 collected data for AL, CCT, ACD, LT and K from the vast majority of eyes. Considering the built‐in QIs improved the measurement variability substantially. Repeatability measurements indicate that clinically meaningful changes can be detected reliably with this instrument.

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Repeatability of a new swept-source optical coherence tomographer and agreement with other three optical biometers

Cited by 25 publications

References 32 publications

Comparison of ocular biometry obtained with Tomey OA-2000 and IOLMaster 700 in silicone oil-filled eyes

Comparison of ocular biometry obtained with Tomey OA-2000 and IOLMaster 700 in silicone oil-filled eyes

Evaluation and comparison of ocular biometric parameters obtained with Tomey OA-2000 in silicone oil-filled aphakia eyes

Feasibility and repeatability of ocular biometry measured with IOLMaster 700 in a large population‐based study

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