“…Similarly, iron, or other metals (such as cadmium), can be bound for storage, detoxification, or function in some other mechanism unrelated to the binding of metals or oxygen ( 49 ). In addition, it has been reported that hemerythrins may play a role in intracellular iron homestatsis, and the repair of iron centers in certain bacteria ( 65 , 66 ). PG_0686 lacks the classic 5 His motif featured in other hemerythrins, and has only one histidine residue predicted to be involved in chloro diiron-oxo binding; as such, it appears to be a part of the group of non-canonical hemerythrin sequences.…”