“…Studies performed from the benchtop to the clinic have provided exciting possibilities for BMP-2 and IGF-1 to stimulate periodontal tissue repair (Vainio, et al, 1993;Yamaguchi, 1995;King and Hughes, 2001;Xu, et al, 2003;Fujiwara, et al, 2005;Ripamonti, et al, 2005;Popowics, et al, 2005;Soares, et al, 2005;Kaigler, et al, 2006).…”