Repair of Anterior Staphyloma with Dehydrated Dura Mater Patch Graft

Yalçındağ, F Nilüfer; Çelik, Selcen; Özdemir, Oya

doi:10.3928/15428877-20080701-19

Cited by 9 publications

(8 citation statements)

References 7 publications

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“…It is unable to withstand the intraocular pressure, and thus, progressively protrudes. The few treatment options in anterior staphyloma include penetrating keratoplasty, sclerokeratoplasty, and dural patch (6)(7)(8) . Besides increased complexity of large graft surgery resulting from loss of limbal support and subsequent protrusion of the lens-iris diaphragm during surgery, the poorer outcomes observed in these types of procedures are multifactorial, including extensive initial infection, postoperative chronic ocular surface and anterior segment inflammation, and secondary glaucoma.…”

Section: Discussionmentioning

confidence: 99%

“…Treatment options in cases of anterior staphyloma include penetrating keratoplasty, mushroom grafts, sclerokeratoplasty, and du ral patch (6)(7)(8) . We report a case of acquired anterior staphyloma following perforation of a corneal ulcer in a patient who used crack cocaine daily for 6 months prior to the second presentation and its management.…”

Section: Introductionmentioning

confidence: 99%

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Acquired anterior staphyloma after corneal ulcer associated with the use of crack

Vasconcelos

Guerra

Morato

et al. 2016

Arquivos Brasileiros De Oftalmologia

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CASE REPORTA 30-year-old black man presented with a 4-week history of a foreign body sensation, redness, and pain in his right eye. His left eye was stable. The patient had a history of crack cocaine and injected heroin abuse. He was homeless and admitted to using crack cocaine daily over the past 4 months. He denied any previous contact lens use, trauma, or ocular surgery. He was otherwise quite well with no systemic symptoms, and his general medical history was unremarkable.On examination at our hospital, uncorrected visual acuity was found to be light perception (LP) in the right eye and 20/25 in the ABSTRACTWe describe an unusual case of acquired anterior staphyloma in a patient addicted to crack cocaine. At the beginning of his crack cocaine abuse, he noticed redness and irritation of his eyes. Over the next 4 months, the patient also noticed the onset of decreasing visual acuity in his right eye (OD). Initially, his visual acuity was light perception in OD, and slit-lamp examination revealed a corneal infiltrate with a peripheral perforation and an iris prolapse. The patient was hospitalized to ensure compliance with the prescribed treatment and was advised to undergo therapeutic keratoplasty; however, the patient left the hospital against medical advice and was lost to follow-up for the next 6 months. He returned with complaints of photophobia and the inability to close his right eyelids. At this time, his cornea had developed an anterior staphyloma and required a sclerokeratoplasty. Following surgery, the patient was again lost to follow-up.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Acquired anterior staphyloma after corneal ulcer associated with the use of crack

Vasconcelos

Guerra

Morato

et al. 2016

Arquivos Brasileiros De Oftalmologia

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“… 1 To reinforce thinned sclera, various materials have been attempted for grafting including allogeneic sclera, amniotic membrane (AM), fascia lata, dura mater, pericardium and periosteum. 2 – 6 However, an ectopic donor tissue such as periosteum, dura mater, or pericardium is hard to obtain; therefore, clinical experience with these has been limited. Among these materials, preserved donor scleral grafts have been preferred for a long time and have produced acceptable outcomes.…”

Section: Introductionmentioning

confidence: 99%

Preserved Corneal Lamellar Grafting Reduces Inflammation and Promotes Wound Healing in a Scleral Defect Rabbit Model

Kim

Ryu

Kim

et al. 2020

Trans. Vis. Sci. Tech.

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Purpose To investigate the effect of preserved corneal lamellar grafting on inflammation and wound healing and to compare its effect with that of preserved scleral grafting in a scleral defect rabbit model. Methods New Zealand White rabbits were assigned to a corneal lamellar grafting group ( n = 5) or a scleral grafting group ( n = 5). After lamellar dissection of superotemporal sclera using 6.0-mm trephine, the same sizes of preserved human corneal or scleral grafts were transplanted with 10-0 nylon interrupted sutures. The grafted areas were photodocumented at 3 to 21 days after surgery to evaluate epithelial wound healing index (%), neovascularization and presence of filaments. The existence of CD3 + T cells and CD34 + cells at the grafted areas was analyzed at 21 days. Results Epithelial wound healing index was significantly higher in the corneal grafting group at 9 days ( P < 0.05). Scleral grafts showed copious formation of filaments adherent to the engrafted area from 9 to 14 days, whereas the corneal grafts were free of filaments. The numbers of inflammatory cells were significantly higher in the scleral grafts ( P < 0.05), and CD3 + T cells and CD34 + cells were populated within inflammatory cells at graft–recipient junctions in both groups. The mean areas of the estimated perigraft and intragraft neovascularization tended to be higher in scleral grafts. Conclusions Preserved corneal lamellar grafting enhances epithelial wound healing and alleviates inflammation in a scleral defect rabbit model. Translational Relevance This work suggests that the preserved corneal graft may be considered as a favorable alternative option for repairing scleral defects.

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“…3 The treatment modalities available in cases of anterior staphyloma include penetrating keratoplasty, mushroom grafts, step grafts, sclerokeratoplasty, and dural patch. [4][5][6][7] The incidence of glaucoma after a routine keratoplasty varies from 9% to 31% in the early postoperative period and from 18% to 35% in the late postoperative period. 8 A study by Goldberg et al 9 found that 71% of patients with preexisting glaucoma had increased pressure develop in the early postoperative course.…”

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confidence: 99%

Structural and Functional Salvaging of Eyes With Anterior Staphyloma Using Cyclodialysis With Penetrating Keratoplasty

Mannan

Sharma

Pruthi

et al. 2012

Cornea

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Repair of Anterior Staphyloma with Dehydrated Dura Mater Patch Graft

Cited by 9 publications

References 7 publications

Acquired anterior staphyloma after corneal ulcer associated with the use of crack

Acquired anterior staphyloma after corneal ulcer associated with the use of crack

Preserved Corneal Lamellar Grafting Reduces Inflammation and Promotes Wound Healing in a Scleral Defect Rabbit Model

Structural and Functional Salvaging of Eyes With Anterior Staphyloma Using Cyclodialysis With Penetrating Keratoplasty

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