Repair in arterial tissue

Christensen, Bent Collatz

doi:10.1007/bf00432203

Cited by 12 publications

(1 citation statement)

References 21 publications

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“…The in vivo studies were carried out in rabbits. Changes in endothelial permeability and the extent of endothelial regeneration after mech anical injury were quantitated by intravenous injection of Evans-blue, an azo-dye known to bind to serum albumin (12). This dye-protein complex actively stains areas of enhanced permeability as well as vessels devoid of endothelium (13).…”

Section: Introductionmentioning

confidence: 99%

In vivo and in vitro Studies on Endothelial Regeneration

Clopath¹,

Müller²,

Stäubli³

et al. 1979

Pathophysiol Haemos Thromb

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Endothelial regeneration was studied in rabbit aorta after intra-arterial balloon catheterization. Most of the regenerated endothelium originated from existing branches which was assessed by the Evans-blue uptake pattern and confirmed by transmission and scanning electron microscopy. Glucocorticoid treatment enhanced re-endothelialization whereas hyperlipemic diet inhibited. Sera from minipigs fed an atherogenic diet consistently have less ability than sera from control pigs to stimulate in vitro the regeneration of wounded endothelium-like monolayers of 3T3-B cells. The deficiency is probably due to an inhibitor which appears and disappears with changes in the diet.

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Section: Introductionmentioning

confidence: 99%