Renin activity in rat choroid plexi: effects of water-deprivation and hypovolemia

Abstract

Choroid plexus contains components of a renin-angiotensin system that could regulate hydration. Hypovolemia or 48 h water deprivation did not change choroidal renin-like activity; but under identical assay conditions, brain perfusion with cold isotonic sucrose containing EDTA and PMSF increased enzyme activity 3-4-fold.