La Réforme en France Et en Italie 2007
DOI: 10.4000/books.efr.1753
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Renata di Francia tra Ferrara e Montargis

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“…Shared common genes between ASD and type 2 DM may increase the risk of type 2 DM in patients with ASD (9,10,(28)(29)(30)(31). GLO1, an enzyme involved in the detoxification of methylglyoxal and in limiting the advanced glycation end products formation, is crucial in autism susceptibility and type 2 DM disease progression (9,10,29,31).…”
Section: Discussionmentioning
confidence: 99%
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“…Shared common genes between ASD and type 2 DM may increase the risk of type 2 DM in patients with ASD (9,10,(28)(29)(30)(31). GLO1, an enzyme involved in the detoxification of methylglyoxal and in limiting the advanced glycation end products formation, is crucial in autism susceptibility and type 2 DM disease progression (9,10,29,31).…”
Section: Discussionmentioning
confidence: 99%
“…GLO1, an enzyme involved in the detoxification of methylglyoxal and in limiting the advanced glycation end products formation, is crucial in autism susceptibility and type 2 DM disease progression (9,10,29,31). In addition, Belligni et al (28) reported that a patient with a de novo duplication on chromosome 17p13.1 involving neuroligin 2, ephrin B3, and GLUT type 4 genes manifested obesity, type 2 DM, intelligence disability, and autistic traits. Additional genome-wide association studies are necessary to identify more susceptible candidate genes for the risk of type 2 DM in patients with ASD.…”
Section: Discussionmentioning
confidence: 99%