Renal transplantation in a HIV positive patient

Abstract

Historically HIV positive patients were considered a contraindication for renal transplant. After the year 1996, with the introduction of HAART the retropositive patients live longer and therefore end stage organ disease is now an increasingly important cause of mortality and morbidity in these patients. Here we report our experience for the first time in India. A forty nine year old hypertensive female from Africa who was diagnosed chronic kidney disease and retropositive status, progressed to end stage renal disease and underwent live related renal transplant at our centre.

Late post transplant HIV infection with BK viremia and allograft tuberculosis in a renal transplant recipient with Kaposi sarcoma

“…He was switched over to sirolimus monotherapy, which inhibits the progression of dermal Kaposi's sarcoma in kidney-transplant recipients while providing effective immunosuppression. [3] Subsequently, he tested positive for HIV and renal biopsy and nuclear amplification test showed evidence of TB and he was started on antiretroviral therapy and antituberculous drugs. The sensitivity of the nuclear amplification test is 63-95% and the specificity is 96%.…”