Renal Support for Acute Kidney Injury in the Developing World

Annigeri, Rajeev A; Ostermann, Marlies; Tolwani, Ashita J.; Vázquez-Rangel, Armando; Ponce, Daniela; Bagga, Arvind; Chakravarthi, Rajasekara; Mehta, Ravindra L.

doi:10.1016/j.ekir.2017.04.006

Cited by 29 publications

(24 citation statements)

References 133 publications

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“…This high mortality depicts the significant contribution of AKI in neonatal mortality in many lower income countries and calls for efforts to build capacity for appropriate management of children with AKI especially provision of renal replacement therapy. [6].…”

Section: Discussionmentioning

confidence: 99%

“…[5] Most countries in lower and middle income settings including Tanzania have limited facilities and skilled health care providers for provision of care to patients with kidney diseases particularly those requiring renal replacement therapy. [6] International Society of Nephrology through its 0 by 25 initiative declared management of AKI a human right issue promoting elimination of preventable deaths from AKI by 2025. [7,8] In Tanzania, 2.1 million babies were born in 2015, and 39,000 neonates are estimated to have died from birth asphyxia (29.3%), prematurity (24.7%) and sepsis (19.7%) which are the leading causes neonatal mortality.…”

Section: Introductionmentioning

confidence: 99%

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Acute kidney injury among critically ill neonates in a tertiary hospital in Tanzania; Prevalence, risk factors and outcome

2020

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Background Neonatal acute kidney injury contributes to high mortality in developing countries. The burden of neonatal AKI is not known in Tanzania despite having high neonatal mortality. This study was conducted to determine the burden of AKI among critically ill neonates admitted at Muhimbili National Hospital. Methods This was a cross-sectional study conducted in the neonatal ward at the MNH. Eligible critically ill neonates were recruited consecutively between October 2017 and March 2018. Data was collected using a standardized structured questionnaire. Blood specimen was drawn to measure baseline creatinine at admission, 48 th hour, 72 nd hour and 14 th day. Data was analysed using SPSS version 20.0 Univariate analysis was done using chi-square to determine the association between categorical variables and multivariate logistic regression was performed to determine predictors of AKI. Results A total of 378 critically ill neonates were recruited, 31.5% had AKI and independent predictors of AKI were noted to be neonatal sepsis (aOR 2.237, 95%CI 1.3-3.6, P = 0.001), severe pneumonia (aOR3.0, 95%CI 1.0-9.3, P = 0.047) and use of gentamycin (aOR6.8, 95%CI 1.3-9.3, P = 0.02). Complete resolution of renal dysfunction at the fourteenth day was seen in 83.1% of the neonates while 16.9% had persistence of renal dysfunction. Ultrasound scan were performed among 105 participants with AKI revealed increased echogenicity, mild hydronephrosis and ectopic kidneys in 25 (23.8%), 4 (3.8%) and 2 (1.9%) respectively. In-hospital mortality was significantly higher among neonates with AKI (70.6%) as compared to those without (29.4%) p< 0.001.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Acute kidney injury among critically ill neonates in a tertiary hospital in Tanzania; Prevalence, risk factors and outcome

2020

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“…The dialysis has two methodologies in major: hemodialysis and peritoneal dialysis [6]. The hemodialysis is a process of performing dialysis with dialyser chamber and the ultrafiltration is done in dialyser chamber by taking blood outside the body and electrolyte exchange is also performed [14]. AV fistula surgery and AV graft is done for long term dialysis [21].…”

Section: Existing Solutionmentioning

confidence: 99%

Design and Development of the Novel Technology for the Treatment of Patients with the Acute and Chronic Renal Failure

2019

IJITEE

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Kidney failure is a condition where the function of kidney gets disabled. In order to sustain in life, dialysis is predominantly adopted. The dialysis is a technical replacement of function of kidney and it is of two types. In considering the long term blood filtering process, the hemodialysis will be an efficient device in replacing the renal functioning but it was currently performed in the stationary mode. In order to fulfill the life supporting requirement, the “Miniaturized portable hemodialysis” device has been introduced which will be portable than the conventional ones. In order to enhance their features, the chambered dialysate technology and the specialized filtering mechanism has been fabricated to this project device. In the process of rectifying the technical errors, sensor indications are implemented for safety measures. In focusing towards the portable mechanism, the battery backup has been applied in this device which can perform patient dialysis in transferable mode.

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“…Rajeev A. Annigeri et. al., have discussed about the data for advancement in medications of the acute kidney injury [16]. The acute renal medication does not require fistula process.…”

Section: Paper Surveymentioning

confidence: 99%

Design of Mobile Hemodialysis Apparatus for Acute Renal Failure Patient's Self-Help and Treatment Adherence

2019

ijrte

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The major intend of the nephrologists is to reduce the hardships faced by the patients affected with renal ailments. Kidney failure or renal failure is a condition where the function of kidney gets disabled/affected at large. This condition may neither be temporary or lifelong but in order to sustain in life, dialysis was adopted. The dialysis is a technical replacement of function of kidney and its process has two sectors; peritoneal dialysis and hemodialysis. In considering the long term blood filtering process, the hemodialysis will be an efficient device in replacing the renal functioning, but it was currently performed in the stable mode. In undergoing the deep survey, our team has analyzed that the major problem in the dialysis is the duration, cost, difficulties faced by the patients. In order to overcome these barriers, the prototype of the portable technology has been built for highly supporting the patients. In order to fulfill the life supporting requirement, the “Miniaturized portable hemodialysis” device has been introduced which will be portable than the conventional ones.

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Renal Support for Acute Kidney Injury in the Developing World

Cited by 29 publications

References 133 publications

Acute kidney injury among critically ill neonates in a tertiary hospital in Tanzania; Prevalence, risk factors and outcome

Acute kidney injury among critically ill neonates in a tertiary hospital in Tanzania; Prevalence, risk factors and outcome

Design and Development of the Novel Technology for the Treatment of Patients with the Acute and Chronic Renal Failure

Design of Mobile Hemodialysis Apparatus for Acute Renal Failure Patient's Self-Help and Treatment Adherence

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