Renal Sarcoidosis and Multiple Myeloma

Abstract

An association between sarcoidosis and multiple myeloma (MM) has been reported in several case reports. In these cases, sarcoidosis is chronically active, systemic, diagnosed at a later age than controlled groups, and often precedes the diagnosis of multiple myeloma by several years. We present the first case of a 43-year-old asymptomatic man with abnormal renal function and monoclonal gammopathy who was simultaneously diagnosed with renal sarcoidosis and MM. He was successfully treated with Thalidomide and steroids and remains in remission after two years of follow up. Pathophysiology of sarcoidosis and MM with special focus on potential link between the two diseases is discussed.