Renal replacement therapy in Europe: a summary of the 2013 ERA-EDTA Registry Annual Report with a focus on diabetes mellitus

Abstract

BackgroundThis article provides a summary of the 2013 European Renal Association–European Dialysis and Transplant Association (ERA-EDTA) Registry Annual Report (available at ), with a focus on patients with diabetes mellitus (DM) as the cause of end-stage renal disease (ESRD).MethodsIn 2015, the ERA-EDTA Registry received data on renal replacement therapy (RRT) for ESRD from 49 national or regional renal registries in 34 countries in Europe and bordering the Mediterranean Sea. Individual patient data were provided by 31 registries, while 18 registries provided aggregated data. The total population covered by the participating registries comprised 650 million people.ResultsIn total, 72 933 patients started RRT for ESRD within the countries and regions reporting to the ERA-EDTA Registry, resulting in an overall incidence of 112 per million population (pmp). The overall prevalence on 31 December 2013 was 738 pmp (n = 478 990). Patients with DM as the cause of ESRD comprised 24% of the incident RRT patients (26 pmp) and 17% of the prevalent RRT patients (122 pmp). When compared with the USA, the incidence of patients starting RRT pmp secondary to DM in Europe was five times lower and the incidence of RRT due to other causes of ESRD was two times lower. Overall, 19 426 kidney transplants were performed (30 pmp). The 5-year adjusted survival for all RRT patients was 60.9% [95% confidence interval (CI) 60.5–61.3] and 50.6% (95% CI 49.9–51.2) for patients with DM as the cause of ESRD.

International differences in chronic kidney disease prevalence: a key public health and epidemiologic research issue

“…For the purpose of this review we used data on the implementation of the following national response systems per country, comprising an operational (multisectorial) national policy, strategy or action plan (1) that integrates several noncommunicable diseases and shared risk factors; (2) to reduce the harmful use of alcohol; (3) to reduce physical inactivity and/or promote physical activity; (4) to reduce the burden of tobacco use; or (5) to reduce unhealthy diet and/or promote healthy diets. Each country received a score, ranging from 0 to 5, based on the number of incorporated national response systems.…”

“…The number of patients starting renal replacement therapy (RRT) due to ESRD varies from less than 30 to more than 200 people per million population across European countries and is much higher in most highincome countries compared to countries where access to health care is limited [4]. RRT has a significant impact on both individual patient quality of life [5,6] and health system budgets [7,8].…”

End-Stage Renal Disease versus Death in a Portuguese Cohort of Elderly Patients: An Approach using Competing Event Analysis

“…Portugal has the highest unadjusted incidence and prevalence of ESRD among European countries4 and 67.7% of the incident dialysis patients, in 2015, were over 65 years with a mean age of prevalent patients of 66.7 years 5…”

The Impact of Inflammation on Cognitive Impairment in Chronic Kidney Disease Patients

“…Although during the last decades the technology and the effectiveness of HD therapy have improved, HD therapy still induces numerous implications, which are responsible, to some extent, for the significant clinical problems that CKD patients experience. Furthermore, according to the ERA-EDTA annual report of 2013, it was estimated that the 5-year adjusted survival of all patients who received the HD therapy was 60.9% [3].…”