Renal mucinous tubular and spindle cell carcinoma

Abstract

We report a case of mucinous tubular and spindle cell carcinoma in a 66-yearold woman. The tumour, located on the left kidney, was well circumscribed. Microscopically, the tumour was composed of cuboidal cells arranged in tubules and making abrupt transitions to spindle cell morphology in a myxoid stroma. Tumour cells were strongly positive for cytokeratin 7 and epithelial membrane antigen. Because of the favourable prognosis with this type of tumour, mucinous tubular and spindle cell carcinoma must be differentiated from papillary renal cell carcinoma, especially that with sarcomatoid change. No tumour recurrence or metastasis were reported with a follow-up of 23 months.

Mucinous tubular and spindle cell carcinoma

“…[3, 3, 5, 11] This was also true of this patient, who has developed a large mass of tumor before any symptoms were noted.…”

Mucinous Tubular and Spindle Cell Carcinoma

“…[3,4,5,11] This was also true of this patient, who has developed a large mass of tumor before any symptoms were noted.…”

“…Patients with sarcomatoid and disseminated disease have much worse prognosis than those with the classic type, even when large tumors confined to the kidney are discovered [1][2][3][4][5][6][7][8]. The main treatment method up till now remains radical nephrectomy, even in cases of disseminated disease [7,11]. Usually they do not require adjuvant treatment [1,11].…”

Mucinous Tubular and Spindle Cell Carcinoma of the Kidney

“…[26][27][28] And fortunately our patient underwent a conservative surgical treatment, which resulted to be the most appropriate for this indolent kind of tumor.…”