Renal, metabolic and hematological effects of trans-retinoic acid during critical developmental windows in the embryonic chicken

Alvine, Travis; Burggren, Warren W.

doi:10.1007/s00360-013-0777-9

Cited by 2 publications

(1 citation statement)

References 42 publications

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“…Currently, investigators typically describe a critical window as a specific, defined period during development when G × E × D (and, studied less often, [G × (E + Epi) × D] interactions result in subsequently switched (modified) phenotypes that differ from the normally expected range of developmental trajectory. Numerous authors have offered up similar definitions -e.g., Kunes and Zicha (2006), Ferner and Mortola (2009), Ali et al (2011), Burggren and Reyna (2011), Vickers (2011), Voss (2013), Alvine and Burggren (2014), , Burggren and Mueller (2015), Eme et al (2015), and Pelster and Burggren (2018).…”

Section: Critical Windows Developmental Plasticity and Phenotype Swmentioning

confidence: 99%

Phenotypic Switching Resulting From Developmental Plasticity: Fixed or Reversible?

Burggren

2020

Front. Physiol.

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The prevalent view of developmental phenotypic switching holds that phenotype modifications occurring during critical windows of development are "irreversible"that is, once produced by environmental perturbation, the consequent juvenile and/or adult phenotypes are indelibly modified. Certainly, many such changes appear to be non-reversible later in life. Yet, whether animals with switched phenotypes during early development are unable to return to a normal range of adult phenotypes, or whether they do not experience the specific environmental conditions necessary for them to switch back to the normal range of adult phenotypes, remains an open question. Moreover, developmental critical windows are typically brief, early periods punctuating a much longer period of overall development. This leaves open additional developmental time for reversal (correction) of a switched phenotype resulting from an adverse environment early in development. Such reversal could occur from right after the critical window "closes," all the way into adulthood. In fact, examples abound of the capacity to return to normal adult phenotypes following phenotypic changes enabled by earlier developmental plasticity. Such examples include cold tolerance in the fruit fly, developmental switching of mouth formation in a nematode, organization of the spinal cord of larval zebrafish, camouflage pigmentation formation in larval newts, respiratory chemosensitivity in frogs, temperature-metabolism relations in turtles, development of vascular smooth muscle and kidney tissue in mammals, hatching/birth weight in numerous vertebrates,. More extreme cases of actual reversal (not just correction) occur in invertebrates (e.g., hydrozoans, barnacles) that actually 'backtrack' along normal developmental trajectories from adults back to earlier developmental stages. While developmental phenotypic switching is often viewed as a permanent deviation from the normal range of developmental plans, the concept of developmental phenotypic switching should be expanded to include sufficient plasticity allowing subsequent correction resulting in the normal adult phenotype.

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Section: Critical Windows Developmental Plasticity and Phenotype Swmentioning

confidence: 99%

Phenotypic Switching Resulting From Developmental Plasticity: Fixed or Reversible?

Burggren

2020

Front. Physiol.

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Altered embryonic development in northern bobwhite quail (Colinus virginianus) induced by pre-incubation oscillatory thermal stresses mimicking global warming predictions

Reyna

Burggren

2017

PLoS ONE

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Global warming is likely to alter reproductive success of ground-nesting birds that lay eggs normally left unattended for days or even weeks before actual parental incubation, especially in already warm climates. The native North American bobwhite quail (Colinus virginianus) is such a species, and pre-incubation quail eggs may experience temperatures ≥45°C. Yet, almost nothing is known about embryonic survival after such high pre-incubation temperatures. Freshly laid bobwhite quail eggs were exposed during a 12 day pre-incubation period to one of five thermal regimes: low oscillating temperatures (25–40°C, mean = 28.9°C), high oscillating temperatures (30–45°C, mean = 33.9°C), low constant temperatures (28.85°C), high constant temperatures (mean = 33.9°C), or commercially employed pre-incubation temperatures (20°C). After treatment, eggs were then incubated at a standard 37.5°C to determine subsequent effects on embryonic development rate, survival, water loss, hatching, and embryonic oxygen consumption. Both quantity of heating degree hours during pre-incubation and specific thermal regime (oscillating vs. non-oscillating) profoundly affected important aspects of embryo survival and indices of development and growth Pre-incubation quail eggs showed a remarkable tolerance to constant high temperatures (up to 45°C), surviving for 4.5±0.3 days of subsequent incubation, but high oscillating pre-incubation temperature increased embryo survival (mean survival 12.2±1.8 days) and led to more rapid development than high constant temperature (maximum 38.5°C), even though both groups experienced the same total heating degree-hours. Oxygen consumption was ~200–300 μl O2.egg.min-1 at hatching in all groups, and was not affected by pre-incubation conditions. Oscillating temperatures, which are the norm for pre-incubation quail eggs in their natural habitat, thus enhanced survival at higher temperatures. However, a 5°C increase in pre-incubation temperature, which equates to the predicted long-term increases of 5°C or more, nonetheless reduced hatching rate by approximately 50%. Thus, while pre-incubation bobwhite eggs may be resiliant to moderate oscillating temperature increases, global warming will likely severely impact wild bobwhite quail populations, especially in their strongholds in southern latitudes.

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Renal, metabolic and hematological effects of trans-retinoic acid during critical developmental windows in the embryonic chicken

Cited by 2 publications

References 42 publications

Phenotypic Switching Resulting From Developmental Plasticity: Fixed or Reversible?

Phenotypic Switching Resulting From Developmental Plasticity: Fixed or Reversible?

Altered embryonic development in northern bobwhite quail (Colinus virginianus) induced by pre-incubation oscillatory thermal stresses mimicking global warming predictions

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