Renal Function Impairment in Peripheral Arterial Disease: An Important Parameter that Should not Be Neglected

Screening for peripheral artery disease in dialysis patients: an opportunity for early disease detection and timely initiation of appropriate therapeutic measures

“…A recent comprehensive review demonstrated that 27-36% of patients with PAD also have concomitant impaired renal function [5]. The presence of impaired renal function in these individuals is associated not only with higher morbidity and mortality rates but also with the occurrence of cardiovascular events (stroke, myocardial infarction, and cardiovascular death) [5].…”

“…A recent comprehensive review demonstrated that 27-36% of patients with PAD also have concomitant impaired renal function [5]. The presence of impaired renal function in these individuals is associated not only with higher morbidity and mortality rates but also with the occurrence of cardiovascular events (stroke, myocardial infarction, and cardiovascular death) [5]. Furthermore, impaired renal function negatively affects survival, limb salvage and graft patency rates when these individuals undergo lower extremity revascularization procedures [5].…”

“…The presence of impaired renal function in these individuals is associated not only with higher morbidity and mortality rates but also with the occurrence of cardiovascular events (stroke, myocardial infarction, and cardiovascular death) [5]. Furthermore, impaired renal function negatively affects survival, limb salvage and graft patency rates when these individuals undergo lower extremity revascularization procedures [5]. Conversely, patients on chronic dialysis have high atherosclerosis and arteriosclerosis rates [6]; the increased arterial stiffness is responsible for the high prevalence of carotid artery stenosis, myocardial infarction, PAD, and stroke in this population [6].…”

Clinical Factors and Anticoagulation Level That Determine the Sudden Loss of Kidney Function in Patients Long-Taking Warfarin (A 5-Year Prospective, Observational Study)

“…Так, в исследо-ваниях [36,37] была показана связь перифе-рического атеросклероза с развитием ХБП, а по результатам работы [38] предиктором снижения СКФ оказалась ИБС, наличие кото-рой повышало риск развития тяжелой ХБП более чем в 2 раза.…”

Multifactorial treatment for improvement of renal function and cardiovascular risk: an ATTEMPT for patients with metabolic syndrome and chronic kidney disease

“…Recent metaanalyses found that eGFR (negatively) and albuminuria (positively) were associated with all-cause and CVD mortality, independently of each other and of CVD risk factors, in both the general population 9 and patients with high-risk for CKD (i.e., individuals with DM, hypertension or CVD) 10 . Furthermore, renal dysfunction in patients with CVD or CVD equivalents [such as DM, peripheral artery disease (PAD) or carotid atherosclerosis] seems to increase the occurrence of CVD events or deaths [11][12][13][14][15][16][17][18] . Such findings led to the recognition of CKD, defined as eGFR 560 ml/min/1.73 m 2 , as a CVD risk factor 19 .…”