Renal failure in septic shock: predictive value of Doppler-based renal arterial resistive index

Lerolle, Nicolas; Guérot, Emmanuel; Faisy, Christophe; Bornstain, Caroline; Diehl, Jean‐Luc; Fagon, Jean-Yves

doi:10.1007/s00134-006-0360-x

Cited by 187 publications

(170 citation statements)

References 27 publications

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“…We did not assess the use of the lowest SCr level during admission for estimating baseline kidney function, as performed in other studies (5,11,22). This method of estimating baseline SCr is an alternative for use in retrospective studies, whereas we sought to evaluate methods of classifying patients by pRIFLE criteria prospectively.…”

Section: Discussionmentioning

confidence: 99%

Ascertainment and Epidemiology of Acute Kidney Injury Varies with Definition Interpretation

Zappitelli

Parikh

Akcan-Arikan

et al. 2008

Clinical Journal of the American Society of Nephrology

310

258

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Results: pRIFLE ⌬SCr and AKIN led to identical AKI distributions. pRIFLE ⌬CCl resulted in 14.5% (critically ill) and 11% (noncritical) more patients diagnosed with AKI compared to other methods (P 0.05). Different bSCr estimates led to differences in AKI incidence, from 12% (AdmSCr) to 87.8% (NormsMin) (P 0.05) in the critically ill group and from 4.6% (eCCl 100 ) to 43.1% (NormsMin) (P 0.05) in the noncritical group.Conclusions: AKI definition variation causes interstudy heterogeneity. AKI definition should be standardized so that results can be compared across studies.

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Section: Discussionmentioning

confidence: 99%

Ascertainment and Epidemiology of Acute Kidney Injury Varies with Definition Interpretation

Zappitelli

Parikh

Akcan-Arikan

et al. 2008

Clinical Journal of the American Society of Nephrology

310

258

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“…Lerolle et al [29] showed that patients who developed renal dysfunction exhibited on the admission higher RRI values than those who did not develop it (0.77 vs 0.68, respectively, P \ 0.001). A RRI[0.74 at inclusion had a sensitivity of 78 % (95 % CI 52-94 %), a specificity of 77 % (95 % CI 50-93 %) for severe renal dysfunction (Class I or F according to RIFLE classification).…”

Section: Rri and Akimentioning

confidence: 99%

Doppler ultrasound in kidney diseases: a key parameter in clinical long-term follow-up

Spatola

Andrulli

2016

J Ultrasound

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Doppler ultrasound has been extensively used in detecting reno-vascular diseases, showing to be a noninvasive, safe, low cost and repeatable tool. The Renal Resistive Index (RRI) [(peak systolic velocity -end diastolic velocity)/peak systolic velocity] is a semi-quantitative index derived by Doppler evaluation of renal vascular bed. Normally RRI is in the range of 0.47-0.70, it increases with aging and, usually, it shows a difference between the two kidneys less than 5-8 %. RRI is an important prognostic marker in chronic kidney diseases (CKD), both in diabetic and non-diabetic kidney diseases, because, in longitudinal prospective studies, it significantly correlated with hemodynamic (ABPM, SBP, DBP, pulse pressure) and histopathological parameters (glomerular sclerosis, arteriolosclerosis, interstitial fibrosis/tubular atrophy, interstitial infiltration). In acute kidney injury (AKI) RI is a valid tool in differentiating between pre-renal and renal failure and in predicting renal response to vasoactive agents. In addition a RRI[0.74 can predict the onset of AKI in septic patients. Renal Resistive Index is a useful marker in allograft diseases because it has been widely showed a correlation with histological lesions during worsening of renal function, both in acute rejection and in chronic allograft nephropathy. Recent studies suggest its role in the risk of new onset diabetes after transplantation and it could be one of the parameters to evaluate to shift or withdrawal immunological and/or hypertensive therapy.Keywords Renal resistive index Á Diabetic nephropathy Á Acute kidney injury Á Renal transplantation Á Chronic kidney diseaseRiassunto La Metodica Color Doppler è stata diffusamente utilizzata per evidenziare patologie nefrovascolari in relazione alle caratteristiche di non invasività, sicurezza, basso costo e ripetibilità della stessa. L'indice di resistenza renale (RRI) [(Picco di velocità sistolica -Velocità telediastolica)/ Picco di velocità sistolica] è un indice semiquantitativo derivato dalla valutazione Doppler del letto vascolare renale. Normalmente il valore del RRI è nel range di 0,47-0,70, aumentando con l'età, e usualmente, è presente una differenza tra i due reni inferiore al 5-8%. RRI è un importante marker prognostico nelle patologie renali croniche (CKD), sia diabetiche che non-diabetiche, poichè, in studi prospettici longitudinali, esso correla significativamente con parametri emodinamici (ABPM, Pressione Sistolica, pressione Diastolica, Pressione di Polso) e istopatologici (glomerulosclerosi, arteriolosclerosi, fibrosi interstiziale/ atrofia tubulare e infiltrato interstiziale). Nel Danno Renale Acuto (AKI) RI è un valido strumento nel distinguere l'insufficienza acuta pre-renale da quella renale e nel predire la risposta renale agli agenti vasoattivi. Inoltre un valore di RRI [0,74 può predire la comparsa di AKI nei pazienti affetti da sepsi. RRI è un marker utile nelle patologie del rene trapiantato, perchè è stata ampiamente dimostrata una correlazione con lesioni istologiche...

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“…25 A threshold of RI has been proposed to detect the risk of acute kidney injury 29 and may help to adjust therapeutic modalities for perfusion at the bedside. 30 The RBF increase during infusion of a "renal dopamine dose" at day 6 is associated with vasodilatation reflected by RI decrease.…”

Section: Discussionmentioning

confidence: 99%

Untitled

Bataille

Payen²,

Villiers³

et al. 2016

Exp Clin Transplant

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Objectives: The relation between dopamine infusion and renal hemodynamics and function has not been studied in renal allografts during early recovery. We analyzed the dose response of dopamine infusion on renal blood flow and function in human kidney transplant recipients at reperfusion and during early graft recovery. Conclusions: Immediately after transplant, kidney grafts with ischemic-reperfusion injury are fully dilated and do not respond to dopamine. The specific renal effects observed are due to systemic hemodynamic status. Vascular responsiveness to a "renal dopamine dose" returns on graft recovery.

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Renal failure in septic shock: predictive value of Doppler-based renal arterial resistive index

Abstract: Doppler-based determination of RI on D1 in septic shock patients may help identify those who will develop ARF.

Cited by 187 publications

References 27 publications

Ascertainment and Epidemiology of Acute Kidney Injury Varies with Definition Interpretation

Ascertainment and Epidemiology of Acute Kidney Injury Varies with Definition Interpretation

Doppler ultrasound in kidney diseases: a key parameter in clinical long-term follow-up

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