Renal failure due to peri-ureteric fibrosis

Ross, J. Cosbie; Tinckler, L. F.

doi:10.1002/bjs.18004619510

Cited by 55 publications

(23 citation statements)

References 14 publications

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“…The first use of oral steroids in the treatment of RPF was described in 1958 [16]. Our starting dose of approximately 30 mg/day is at the lower range of that recommended or utilised in recent literature (generally 30–60 mg/day) [1, 6, 11, 13].…”

Section: Discussionmentioning

confidence: 99%

Successful Use of Steroids and Ureteric Stents in 24 Patients with Idiopathic Retroperitoneal Fibrosis: A Retrospective Study

et al. 2008

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Background/Aims: Retroperitoneal fibrosis (RPF) is a chronic inflammatory disorder causing obstructive nephropathy and renal failure. We reviewed our management of this condition. Method: All patients with RPF treated at a single center over a 15-year period were identified. A full review of notes and computer records was undertaken. Results: Data was available on 27 patients, 3 of which were excluded from later analysis. Diagnosis was based on clinical history and cross-sectional imaging. Retroperitoneal biopsy was undertaken in 3 patients. 96% had significant renal impairment at presentation with a mean serum creatinine of 688 µmol/l. 46% required emergency hemodialysis. All patients were treated with a combination of ureteric stents and/or steroids with an excellent clinical response. The mean best creatinine reached by the cohort was 136 µmol/l, and renal function remained stable in the long term. No patients required chronic dialysis. Ureteric stents were removed within 12 months and low-dose steroids were continued for a mean of 34 months. Recurrent disease was observed in 25% of patients, who all responded well to further steroid therapy. Mean duration of follow-up was 76 months. Conclusions: RPF is very effectively treated by a combination of ureteric stents and steroids, with excellent long-term results using this approach. Continued follow-up is advised because of the possibility of recurrent disease.

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Section: Discussionmentioning

confidence: 99%

Successful Use of Steroids and Ureteric Stents in 24 Patients with Idiopathic Retroperitoneal Fibrosis: A Retrospective Study

et al. 2008

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“…In the case of failure to respond to medical treatment, the treatment approach is adjuvant CS therapy after surgical obstruction is reduced by ureterolysis. Secondary RF is treated for the underlying cause (8). Urinary system decompression was achieved by DJ stent in two of our patients, by PNT in three patients and by both DJ stent and PNT placement in five other patients.…”

Section: Discussionmentioning

confidence: 84%

“…Diagnosis of idiopathic RF is generally delayed due to atypical symptoms of the disease and patients may be diagnosed with postrenal ARF in ED. Urologically, the most frequent and most serious complication of the disease is ARF due to bilateral ureteral obstruction (8,9). In two large studies in the literature, pain was the most common presenting symptom, and additionally undefined symptoms such as fatigue, weakness, myalgia were observed (4, 10).…”

Section: Discussionmentioning

confidence: 99%

A rare cause of acute post renal failure: Retroperitoneal fibrosis

Şeker

Ekşi

Çolakoğlu

et al. 2017

Arch Ital Urol Androl

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“…RPF'nin ciddi ve sık rastlanan komplikasyonu üreteral obstrüksiyo-na bağlı, genellikle iki taraflı gelişen hidronefroz ve renal yetersizliktir. [7] Otoimmün hastalık olarak dü-şünülür ancak spesifik immünolojik markerler negatiftir. CRP, ESR gibi nonspesifik belirteçler hastalık aktivitesi ve tedavi yanıtını belirlemesi açısından yararlıdır.…”

Section: Discussionunclassified

Bilateral Hydronephrosis Related To Retroperitoneal Fibrozis and Response To Steroid Therapy

Güllü¹,

Dağel²,

Doğan³

et al. 2011

Istanbul Tip Derg

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ÖZETRetroperitoneal fibrozis (RPF) steroid tedavisine sıklık-la yanıt veren kronik enflamatuvar hastalıktır. Bu yazıda, anüri nedeni ile başvuran, RPF'ye bağlı bilateral hidronefrozu tespit edilen ve steroide çok hızlı yanıt veren bir olgu sunuldu. Altmış beş yaşında erkek hasta, üç gündür idrar yapamama yakınması ile başvurdu. Laboratuvar testlerinde üre: 156 mg/dl, kreatinin: 15 mg/dl idi. Karın bilgisayarlı tomografisinde (BT) retroperitenal mesafede paraaortik alanlarda yaygın yumuşak doku yoğunluk artışı ve bilateral üreteral dilatasyon izlendi ve retroperitoneal fibrozis olarak yorumlandı. Hastaya duble J (DJ) kateter takıldı ve metilprednizolon 60 mg/gün başlandı. İşlem sonrası 7. gün üre 32 mg/dl, kreatinin 1.1 mg/dl ölçüldü. İki ay sonra BT kontrolünde RPF'nin gerilediği izlendi. Hastanın DJ kateteri çekildi ve steroid tedavisi azaltılarak, altıncı ayda kesildi. RPF, obstrüktif üropatinin etyolojik sebepleri arasında akılda tutulmalıdır.Anahtar sözcükler: Böbrek yetmezliği; hidronefroz; retroperitoneal fibrozis; metilprednizolon. SUMMARY Retroperitoneal fibrosis (RPF) is a chronic inflammatory dis-

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Renal failure due to peri-ureteric fibrosis

Cited by 55 publications

References 14 publications

Successful Use of Steroids and Ureteric Stents in 24 Patients with Idiopathic Retroperitoneal Fibrosis: A Retrospective Study

Successful Use of Steroids and Ureteric Stents in 24 Patients with Idiopathic Retroperitoneal Fibrosis: A Retrospective Study

A rare cause of acute post renal failure: Retroperitoneal fibrosis

Bilateral Hydronephrosis Related To Retroperitoneal Fibrozis and Response To Steroid Therapy

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