Renal Epithelial Mitochondria: Implications for Hypertensive Kidney Disease
Krisztian Stadler,
Daria V. Ilatovskaya
Abstract:According to the Centers for Disease Control and Prevention, 1 in 2 U.S. adults have hypertension, and more than 1 in 7 chronic kidney disease. In fact, hypertension is the second leading cause of kidney failure in the United States; it is a complex disease characterized by, leading to, and caused by renal dysfunction. It is well‐established that hypertensive renal damage is accompanied by mitochondrial damage and oxidative stress, which are differentially regulated and manifested along the nephron due to the … Show more
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