2006
DOI: 10.1097/01.pap.0000201831.77472.d3
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Renal Cystic Diseases

Abstract: This review aims to assist in the categorization of inherited, developmental, and acquired cystic disease of the kidney as well as to provide a pertinent, up-to-date bibliography. The conditions included are autosomal-dominant polycystic kidney disease, autosomal-recessive polycystic kidney disease, unilateral renal cystic disease (localized cystic disease), renal simple cysts, multicystic dysplastic kidney, pluricystic kidney of the multiple malformation syndromes, juvenile nephronophthisis and medullary cyst… Show more

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Cited by 227 publications
(230 citation statements)
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“…[8][9][10] Simple renal cyst is the most common structural abnormality observed in human kidneys, with prevalence ranging from 5-41%. 11,12 Similarly to what is seen with AAA, the prevalence of SRCs increases with age and in male population. 13 The majority of SRCs are asymptomatic, not harmful and incidentally found by renal imaging, including computed tomography (CT) and ultrasonography.…”
Section: Introductionmentioning
confidence: 90%
See 1 more Smart Citation
“…[8][9][10] Simple renal cyst is the most common structural abnormality observed in human kidneys, with prevalence ranging from 5-41%. 11,12 Similarly to what is seen with AAA, the prevalence of SRCs increases with age and in male population. 13 The majority of SRCs are asymptomatic, not harmful and incidentally found by renal imaging, including computed tomography (CT) and ultrasonography.…”
Section: Introductionmentioning
confidence: 90%
“…Most SRCs are clinically irrelevant and seldom require treatment. 11,13 Some authors hypothesized that AAA and SRC might share common pathophysiological mechanisms, including possible manifestation of connective tissue weakness. 14 Furthermore, the association between SCRs and AAA might be of clinical importance for the early recognition of patients at risk for the aortic aneurysmal disease.…”
Section: Introductionmentioning
confidence: 99%
“…36 Simple cysts likely originate from the distal convoluted or collecting duct and are thought to arise from renal tubular diverticula, or from tubular cell hyperplasia secondary to nephron loss. [37][38][39] Previous studies in healthy subjects described associations between hypertension and benign renal cysts. [40][41][42] In a cross-sectional analysis of hospitalized patients without overt renal disease undergoing an abdominal computed tomography scan, the presence of cysts was associated with a reduced renal function estimated by creatinine clearance.…”
Section: Discussionmentioning
confidence: 99%
“…Occasionally, they become symptomatic and might present with abdominal discomfort, flank pain, a palpable mass, or hematuria [8] . These clinical symptoms can be a result of complications (hemorrhage, infection, and rupture), or a complaint because of an enlarging cyst, and clinical symptoms might raise the possibility of an associated malignancy [12][13][14] . However, the relationship between renal cyst and renal malignancy has not been confirmed.…”
Section: Discussionmentioning
confidence: 99%