Renal Cell Carcinoma Metastatic to the Tongue: A Case Report and Review of the Literature

Altuntaş, Ozan Muzaffer; Petekkaya, İbrahim; Süslü, Nilda; Güllü, İbrahi̇m

doi:10.1016/j.joms.2014.12.031

Cited by 17 publications

(11 citation statements)

References 9 publications

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“…Oral metastatic lesions of renal cancer are known to undergo extremely rapid enlargement, which results in severe symptoms and a decline in quality of life. Dysphagia was observed in 17 patients [12] , [20] , [21] , [25] , [30] − [32] , [37] , [38] , [41] , [43] , [45] − [47] , [53] , [56] , [67] (Table 1). Obstruction of the upper airways due to rapid growth of oral metastasis led to tracheotomy in one patient [41] and death in one patient [38].…”

Section: Discussionmentioning

confidence: 99%

Renal Cell Carcinoma Metastasis to the Maxillary Bone: A Case Report and Review of the Literature

Nishii¹,

Shiba²,

Ohsako³

et al. 2020

Preprint

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Background: Metastasis of renal cell carcinoma (RCC) to the oral cavity is rare. Given the poor prognosis of metastatic RCC, treatment choice is difficult. Here, we report a case of RCC metastasis to the maxillary bone, and provide a detailed literature review regarding the patient characteristics, treatments and outcomes of RCC metastasis to the oral cavity.Case presentation: An 89-year-old Japanese man presented with an 8 × 8-mm granulomatous tumor with palpable pulsation in the left upper gingiva, which had been clinically suspected as an arteriovenous malformation. The patient had undergone left nephrectomy for clear cell carcinoma 7 years prior. Pulmonary metastasis had appeared 3 years later. The patient underwent tumor resection of the maxilla after intravascular embolization, and the tumor was histopathologically diagnosed as a metastasis of clear cell RCC to the maxillary bone. Seventeen months after surgery, he died because of pulmonary metastasis without evidence of recurrence in the oral cavity.Conclusion: Our literature review reveals that oral metastatic lesions of renal cancer often exhibit rapid enlargement and cause severe symptoms, such as dysphagia and bleeding. Although oral metastasis of RCC has a poor prognosis due to the presence of concurrent disseminated metastases, surgical therapy may be recommended because of its high local control rate and ability to maintain quality of life.

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Section: Discussionmentioning

confidence: 99%

Renal Cell Carcinoma Metastasis to the Maxillary Bone: A Case Report and Review of the Literature

Nishii¹,

Shiba²,

Ohsako³

et al. 2020

Preprint

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“… Excision. Sunitinib Not known Altuntaş et al ., 2015 [ 21 ] 70/M Renal mass Lungs, lymph nodes, bone Interferon alpha followed by partial glossectomy and sunitinib after progression 7 (alive) Wang et al ., 2016 [ 22 ] 71/F History of nephrectomy 10 years previously. Tumor on the tongue Hilar lymph node, lungs Sunitinib 10 (alive) Lieder et al ., 2017 [ 23 ] 56/unknown Nephrectomy for RCC.…”

Section: Discussionmentioning

confidence: 99%

Lingual metastasis as an initial presentation of renal cell carcinoma: a case report

et al. 2017

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BackgroundRenal cell carcinoma is the third most common tumor that metastasizes to the head and neck, after breast and lung carcinomas. Tongue metastasis as an initial presentation of renal cell carcinoma is extremely rare, and very few cases have been reported. The prognosis is poor. We present a rare case of metastatic renal cell carcinoma that initially presented as a tongue lesion.Case presentationWe report the case of a 55-year-old white man who presented with a large exophytic lesion on his tongue. A biopsy was taken, and pathologic examination showed a poorly differentiated carcinoma including a sarcomatoid component. Subtotal glossectomy with neck dissection were planned, but a positron emission tomographic-computed tomography scan showed a left kidney mass. Immunohistochemical evaluation of the tongue lesion was performed, and it was compatible with metastasis from primary renal cell carcinoma. The biopsy of the renal lesion showed a high-grade unclassified renal cell carcinoma. Although our patient underwent systemic therapy, he died of hemorrhagic complications 3 months after the initiation of therapy.ConclusionTongue lesions require a complete assessment to distinguish a metastasis from a primary cancer in order to give the appropriate treatment.

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“…Koga and colleagues2 observed that the most common sites for skin metastasis were the trunk (40%), scalp (25%) and face (9%). The prevalence of tongue metastases is estimated to be 0.17% 3. Similarly, metastasis to the distal extremities is also rare and represents <0.2% of all metastatic lesions 4.…”

Section: Descriptionmentioning

confidence: 99%

Cutaneous finger and tongue metastases in renal cell carcinoma

et al. 2019

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Renal Cell Carcinoma Metastatic to the Tongue: A Case Report and Review of the Literature

Cited by 17 publications

References 9 publications

Renal Cell Carcinoma Metastasis to the Maxillary Bone: A Case Report and Review of the Literature

Renal Cell Carcinoma Metastasis to the Maxillary Bone: A Case Report and Review of the Literature

Lingual metastasis as an initial presentation of renal cell carcinoma: a case report

Cutaneous finger and tongue metastases in renal cell carcinoma

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