Renal cell carcinoma in children, report of a new case

Abstract

Renal cell carcinoma (RCC) is rare in children and is usually found in late children. We present a case of a 14 year-old boy who presented with right lumbar pain. CT-scan showed a tumor in the upper pole of the right kidney measuring 15 cm. He underwent radical nephrectomy and histopathologic examination revealed RCC. No adjuvant therapy was given. After three years and half, there is no evidence of recurrence.

Pediatric with localized renal cell carcinoma (RCC)

“…Meanwhile, renal cell carcinoma (RCC) is a rare kidney malignancy in pediatric. The incidence of RCC increases with age, peaking between the ages of 9 and 15 years, while Wilm's Tumor reaches its peak incidence at the age of 3 years [9] . Although RCC in pediatric is uncommon, its incidence is approximately 2%-6% of all kidney cancers, accounting for about 0.1%-0.3% of all malignancies in pediatrics.…”

“…Most commonly encountered clinical features are flank pain (57%), hematuria (45%), and mass in the flank (38%). The classical triad is only found in 6% of cases, primarily in advanced-stage cases [ 9 , 13 ]. Radiological examinations have limited diagnostic value as it is challenging to differentiate RCC from other kidney malignancies [12] .…”

“…The prognosis of RCC in pediatrics is similar to that in adults. Several factors influencing prognosis include tumor size, patient's age, the approach of complete excision, the presence or absence of vascular invasion, as well as clinical and pathological staging [9] .…”