Renal Cell and Transitional Cell Carcinoma in a Japanese Population Undergoing Maintenance Dialysis

Abstract

In the Japanese population on dialysis RCC is more common than TCC. Since long-term dialysis is a risk factor for RCC, regular imaging examinations may have contributed to the favorable outcome of our patients on dialysis with RCC. In contrast, the unfavorable outcome of TCC suggests the need for effective diagnostic measures for early detection of TCC in patients on dialysis.

Obesity, Diabetes Mellitus, Hypertension and other Risk Factors for Renal Cell Carcinoma in Japan: A Mini-Review

“…In East Asia, Cheung et al [34] reported that chronic dialysis patients showed a significantly higher incidence and mortality of kidney cancer than general population in Hong Kong while Chien et al [35] found that dialysis patients increased the risk of dying from kidney cancer compared to the general population in Taiwan. In Japan, Satoh et al [11] reported that 38 (0.6%) out of 6201 dialysis patients [12] reported that 44 patients (1.7%) were pathologically diagnosed with renal cell carcinoma in 2,624 dialysis patients between 1993 and 2004. These incidences of kidney cancer among dialysis patients appear higher than the incidence of general population (i.e., 7.1/100,000 for males and 3.1/100,000 [36]).…”

“…These findings suggest that environmental factors (i.e., non-genetic risk factors) may play an important role in the development of kidney cancer. Therefore, we identified relevant studies [4][5][6][7][8][9][10][11][12][13] in the PubMed database using a combination of the search terms "Japan", "kidney cancer", "renal cell carcinoma" and "risk". In the ICHUSHI database (the Japanese database) we used a combination of the search terms "kidney cancer /renal cell carcinoma", and "risk factor" (the last search update on May 2017).…”

“…In this paper, we would like to introduce the result of these studies on the risk factors for kidney cancer in the Japanese population [4][5][6][7][8][9][10][11][12][13][14].…”

“…Satoh et al [11] conducted a retrospective cohort study of 6,201 chronic dialysis patients between 1990 and 2003, while Kojima et al [12] carried out a prospective cohort study of the 2,624 dialysis patients between 1993 and 2004 [12]. The final study is the summary of annual nation-wide questionnaire studies from 1982 to 2004 conducted by the Japanese Society for Dialysis Therapy [13].…”

Expressão de Ciclina D1 em Carcinoma de Células Renais

“…A presença de doença renal cística adquirida, que aumenta em prevalência e gravidade com o tempo de diálise, é considerada o principal fator de risco para CCR nesses pacientes, independente da idade ou da doença de base SATOH;TSUCHIYA;HABUCHI;ISHIYAMA et al, 2005). Observou-se uma diferença entre sexos, na qual os homens apresentaram maior incidência e gravidade das alterações císticas do que as mulheres (MARPLE;MACDOUGALL e CHONKO, 1994).…”