Renal carcinoma with osseous and pulmonary metastases in an Arabian gelding

Rumbaugh, M. L..; Latimer, Federico G.; Porthouse, K. R.; Cho, D. Y.; LeBlanc, Casey J.

doi:10.2746/042516403775467522

Cited by 20 publications

(16 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Two of these horses were evaluated for profound forelimb lameness that, after prolonged diagnostic tests and treatment, were diagnosed with metastatic musculoskeletal neoplasia. 16,17 One horse had neoplastic infiltrates in bones of the proximal forelimb. Radiographic evidence of lytic bone and subsequent bone biopsies yielded a diagnosis of neoplastic infiltrates, likely sarcoma.…”

Section: Discussionmentioning

confidence: 99%

“…Euthanasia was performed without further diagnostic tests but renal involvement was not suspected until necropsy. 17 The other lameness went undiagnosed until skeletal muscle metastasis was observed at necropsy. 16 In the horse that presented with a bleeding, gingival mass, the initial diagnosis was a poorly differentiated gingival carcinoma.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A Retrospective Analysis of Renal Carcinoma in the Horse

Wise

Bryan

Sellon

et al. 2009

Veterinary Internal Medicne

View full text Add to dashboard Cite

Background: Renal carcinoma is a rare tumor of horses. Hypothesis: Presenting complaints and clinical signs of this disease are vague and early diagnosis increases survival time. Animals: Data were collected from the medical records of 4 horses presented to Washington State University as well as the 23 previously published case reports of horses with renal carcinoma.Methods: Retrospective study.Results: Renal carcinoma affects horses of all ages with most cases observed in geldings and Thoroughbreds. The most common presenting complaints are nonspecific and usually do not occur until late in the course of the disease. Routine laboratory results generally are unremarkable with no evidence of renal dysfunction. Urine and peritoneal fluid analyses are consistently abnormal, but the changes usually are nonspecific. Rectal palpation often allows detection of an abnormal kidney or a mass in the area of the kidney. Renal ultrasound examination is the most rewarding imaging procedure, and when combined with renal biopsy, antemortem diagnosis can be achieved. Renal carcinoma is both locally invasive and metastatic, necessitating careful staging for metastasis using thoracic radiography and abdominal ultrasound examination. If the tumor is localized to 1 kidney, nephrectomy is the treatment of choice. No chemotherapy or radiation treatment for renal carcinoma has been reported in the horse. Median survival for this series of cases was 11 days (0 days-1 year).Conclusions and Clinical Importance: Prognosis is poor to grave.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A Retrospective Analysis of Renal Carcinoma in the Horse

Wise

Bryan

Sellon

et al. 2009

Veterinary Internal Medicne

View full text Add to dashboard Cite

show abstract

“…Clinical pathological abnormalities described include anaemia, neutrophilia, hypoglycaemia, thrombocytopenia, hypoalbuminaemia, and increases in blood urea nitrogen and serum creatinine concentrations. Metastatic disease is a common feature with dissemination of the neoplasm to the peritoneum and abdominal organs, liver and lungs, regional lymph nodes, thyroid gland, bone and the oral cavity (Haschek et al 1981;Brown and Holt 1985;Servantie et al 1986;van Mol and Fransen 1986;West et al 1987;Rhind et al 1999;Rumbaugh et al 2003). Human RCCs are recognised to have unusual and unpredictable metastatic patterns resulting in clinically detectable metastases without symptoms relating to the primary tumour (Hadjadj et al 1995;Nakhjavani et al 1997).…”

Section: Discussionmentioning

confidence: 99%

Hand‐assisted laparoscopic nephrectomy in a standing horse for the management of renal cell carcinoma

Hilton¹,

Aleman²,

Maher³

et al. 2008

Equine Veterinary Education

View full text Add to dashboard Cite

Summary An 18‐year‐old Quarter Horse gelding was examined for haematuria of 6 weeks' duration. Rectal examination identified an enlarged left kidney and ultrasonographic examination of the kidney identified grossly abnormal renal architecture. Hand‐assisted laparoscopic nephrectomy was performed following laparoscopic exploration of the abdomen for metastatic disease. A laparoscopic stapling device was successfully used to transect and ligate the renal vasculature and ureter. Histopathological examination of the kidney identified renal cell carcinoma. A 7 month survival was documented following surgery. Unilateral nephrectomy should be considered a therapeutic or palliative procedure for horses with renal cell carcinoma.

show abstract

“…A search of the veterinary literature since 1980 revealed 22 cases of equine renal carcinoma, although only 18 have been described in detail (Berggren 1980;Haschek et al 1981;Pomroy 1981;Brown and Holt 1984;van Amstel et al 1984;Owen et al1986;Servantie et al 1986;van Mol and Fransen 1986;West et al 1987;Rhind et al 1989;Baker et al 2001;Rumbaugh et al 2003;Swain et al 2005;Hilton et al 2008). No breed or sex predispositions are apparent from these cases.…”

Section: Discussionmentioning

confidence: 99%

Renal carcinoma as a cause of sudden death in an aged horse

Knowles

Withers

Day

et al. 2008

Equine Veterinary Education

View full text Add to dashboard Cite

Summary This report describes rupture of a primary renal carcinoma as a cause of sudden death of an aged horse that presented with mild clinical signs of colic. The case is considered in the context of the few reported cases in the veterinary literature. The most striking feature of this case was the absence of prodromal signs prior to a catastrophic rupture of the tumour during a diagnostic work‐up.

show abstract

Renal carcinoma with osseous and pulmonary metastases in an Arabian gelding

Cited by 20 publications

References 7 publications

A Retrospective Analysis of Renal Carcinoma in the Horse

A Retrospective Analysis of Renal Carcinoma in the Horse

Hand‐assisted laparoscopic nephrectomy in a standing horse for the management of renal cell carcinoma

Renal carcinoma as a cause of sudden death in an aged horse

Contact Info

Product

Resources

About