Renal Biopsy Research with Implications for Therapy of Glomerulonephritis

Jargin, Sergei V.

doi:10.2174/157488512804999055

Cited by 3 publications

(3 citation statements)

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“…Biased papers are misleading for research and practice, cause losses of time and money. Wrong concepts are persisting and reappearing, which may result in useless experimentation and application of invasive methods without indications [197,204,205]. Some scientific writers have perfected themselves in tangling their texts, making evaluation increasingly difficult.…”

Section: Discussionmentioning

confidence: 99%

“…Related topics reported previously and not included in this and preceding [1] reviews are doubtful effects of calf hemodialysate and policosanol, invasive procedures and organ biopsies with questionable indications etc. [197,204,205,208,209]. Some of the questions are not entirely clear, so that further research and reviews of the literature are needed.…”

Section: Discussionmentioning

confidence: 99%

“…Editors should publish comments and letters containing sound criticism seeing that the criticized authors don't disregard published comments e.g. [61,197,204,205,208] but comprehensively and objectively discuss all relevant publications. The peer review and publication process should become more transparent, among others, to identify biased reviewers.…”

Section: Current and Future Developmentsmentioning

confidence: 99%

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Scientific Papers and Patents on Substances with Unproven Effects. Part 2

Jargin

2020

DDF

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: Several examples are discussed in this review, where substances without proven effects were proposed for practical use within the scope of evidence-based medicines. The following is discussed here: generalizations of the hormesis concept and its use in support of homeopathy; phytoestrogens and soy products potentially having feminizing effects; glycosaminoglycans for the treatment of osteoarthritis and possibilities of their replacement by diet modifications; flavonoids recommended for the treatment of chronic venous insufficiency and varicose veins; acetylcysteine as a mucolytic agent and its questionable efficiency especially by an oral intake; stem cells and cell therapies. In conclusion, placebo therapies can be beneficial and ethically justifiable but it is not a sufficient reason to publish biased information. Importantly, placebo must be devoid of adverse effects, otherwise, it is named pseudo-placebo. Therapeutic methods with unproven effects should be tested in high-quality research shielded from the funding bias. Some issues discussed in this review are not entirely clear, and the arguments provided here can initiate a constructive discussion.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Current and Future Developmentsmentioning

confidence: 99%

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Scientific Papers and Patents on Substances with Unproven Effects. Part 2

Jargin

2020

DDF

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Scientific Papers and Patents on Substances with Unproven Effects

Jargin

2019

DDF

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It is evident from reviewing scientific literature that the quality of argumentation in some areas of medical research has deteriorated during the last decades. Publication of a series of questionable reliability has continued without making references to the published criticism; examples are discussed in this review. Another tendency is that drugs without proven efficiency are advertised, corresponding products patented and marketed as evidence-based medications. Professional publications are required to register drugs and dietary supplements to obtain permissions for the practical use; and such papers appeared, sometimes being of questionable reliability. Several examples are discussed in this review when substances without proven effects were patented and introduced into practice being supported by publications of questionable reliability. Some of the topics are not entirely clear; and the arguments provided here can induce a constructive discussion.

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Surgical and endoscopic treatment of pulmonary tuberculosis: A report from russia

Jargin

2021

Hamdan Med J

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Renal Biopsy Research with Implications for Therapy of Glomerulonephritis

Cited by 3 publications

References 0 publications

Scientific Papers and Patents on Substances with Unproven Effects. Part 2

Scientific Papers and Patents on Substances with Unproven Effects. Part 2

Scientific Papers and Patents on Substances with Unproven Effects

Surgical and endoscopic treatment of pulmonary tuberculosis: A report from russia

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