Renal architecture of the dogfish Scyliorhinus caniculus (Chondrichthyes, Elasmobranchii)

Hentschel, H.

doi:10.1007/bf00312121

Cited by 19 publications

(42 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Torpedo marmorata (Hentschel and Meyer, 1982;Hentschel et al, 1984Hentschel et al, , 1986Hentschel, 1987;Hentschel and Elger, 1987a;and unpublished results). Several features of the renal circulation of the dogfish, Scyl.…”

Section: Squalus Acanthias Raja Erinacea Raja Ocellata Andmentioning

confidence: 78%

“…fil injections, despite a generally satisfactory cast of other microvascular components (Hentschel, 1987). This…”

Section: Discussionmentioning

confidence: 98%

Section: Gross Morphology Of the Kidney And Histology Of The Nephronmentioning

confidence: 88%

“…caniculus Elger, 1982a,b, 1987a; Elger and Hentschel, 1983;Hentschel, 1987). The occurrence of bundles of different lengths has equally been observed in the dogfish (Hentschel, 1987) and strongly suggests the existence of nephron heterogeneity as related to the age of the nephron population. Minor species-specific differences between the dogfish and the skate concern the configuration of the bundles (secondary structure), which frequently are helically wound in the skate and are folded in the dogfish.…”

Section: Gross Morphology Of the Kidney And Histology Of The Nephronmentioning

confidence: 88%

“…caniculus (L.) (Hentschel, 1987). The tissue containing the Microfil casts was embedded in paraffin with methylsalicylate acting as an intermedium.…”

Section: Histologymentioning

confidence: 99%

See 4 more Smart Citations

Renal blood vascular system in the elasmobranch, Raja erinacea mitchill, in relation to kidney zones

Hentschel

1988

Am. J. Anat.

Self Cite

View full text Add to dashboard Cite

The arrangement and structure of renal blood vessels were studied in a marine skate with injection of silicone rubber and methacrylate resin after intravenous administration of epinephrine and perfusion fixation. The methacrylate casts were investigated with the scanning electron microscope. Histology was performed by light and transmission electron microscopy of serial sections. The course of the blood vessels is described in relation to the renal zones of lateral bundles and mesial tissue. Each nephron performs two loops in the lateral bundles and two coilings in the mesial tissue before it joins the collecting duct system. The lateral bundles contain an elaborate countercurrent arrangement of neck segment, proximal tubule segment PIa, early distal tubule segment, and collecting tubule. Within the bundles, the nephron portions are associated with a blind-ended central vessel, which is connected with the venous sinuses of the mesial tissue. The microcirculatory bed around the bundles is supplied with arterial blood via small bundle arteries that originate from the intrarenal arteries in parallel to the afferent arterioles of the glomeruli. The efferent arterioles of the glomeruli convey their blood to the peritubular sinuses of the mesial tissue, which is largely irrigated with venous blood of the renal portal system. The mesial tissue, containing the proximal tubule segments PIb and PII, intermediate segment, and late distal tubule segment LDTb, receives venous blood from the caudal vein and the lateral musculature via afferent renal and intrarenal veins and from the efferent arterioles of the glomeruli and venules of the microcirculation of the bundles. The sinuses are drained by efferent renal veins via efferent intrarenal veins. By comparing the renal structures of the skate with those of dogfish, a unique type of circulation--as related to nephron segments, renal zones, and fine structure of the wall of the vessels--is revealed in marine elasmobranchs of different evolutionary levels.

show abstract

Section: Squalus Acanthias Raja Erinacea Raja Ocellata Andmentioning

confidence: 78%

“…fil injections, despite a generally satisfactory cast of other microvascular components (Hentschel, 1987). This…”

Section: Discussionmentioning

confidence: 98%

Section: Gross Morphology Of the Kidney And Histology Of The Nephronmentioning

confidence: 88%

Section: Gross Morphology Of the Kidney And Histology Of The Nephronmentioning

confidence: 88%

“…caniculus (L.) (Hentschel, 1987). The tissue containing the Microfil casts was embedded in paraffin with methylsalicylate acting as an intermedium.…”

Section: Histologymentioning

confidence: 99%

See 3 more Smart Citations

Renal blood vascular system in the elasmobranch, Raja erinacea mitchill, in relation to kidney zones

Hentschel

1988

Am. J. Anat.

Self Cite

View full text Add to dashboard Cite

show abstract

Developing nephrons in adolescent dogfish, Scyliorhinus caniculus (L.), with reference to ultrastructure of early stages, histogenesis of the renal countercurrent system, and nephron segmentation in marine elasmobranchs

Hentschel¹

1991

Am. J. Anat.

Self Cite

View full text Add to dashboard Cite

Light and electron microscopy of the excretory kidney of adolescent dogfish, Scyliorhinus caniculus (L.), revealed immature and mature nephrons as well as four developmental stages of nephrons. At stage I the nephron was characterized by a condensed mass of mesenchymal cells in the center of several concentric layers of connective tissue. At stage II of the nephron, the S-shaped body was an elongate cyst with a high prismatic epithelium that was connected by a developing collecting tubule with the collecting duct system. At stage III, the developing nephrons already possess the essential features of the mature nephron but lack complete differentiation. Developing renal corpuscles had one afferent arteriole and two efferent vessels. Developing tubules ran four times between the lateral bundle zone and the mesial tissue zone before they joined the collecting duct system. A continuous sheath of flat cells, encompassing the collecting duct system, extended around the developing lateral bundle. A rudimentary central vessel ran from the developing lateral bundle to the venous sinusoid capillaries between the mesial convolutions. Developmental stage IV was similar to the mature nephron, however, renal corpuscles and tubular segments were smaller than those of mature nephrons. Conclusive evidence for morphological homology of elasmobranch nephron segments and collecting tubule-collecting duct system with those of other vertebrates is provided. The origin and nature of the central vessel and the bundle sheath is clarified. These specific structures of marine elasmobranch kidney supposedly are of great functional relevance for the renal countercurrent system that in turn is essential for ion- and osmo-regulation.

show abstract

Heterogenous distribution of glycoconjugates in the kidney of dogfish Scyliorhinus caniculus (l.) with reference to changes in the glycosylation pattern during ontogenetic development of the nephron

Hentschel

Walther

1993

Anat. Rec.

Self Cite

View full text Add to dashboard Cite

Eight fluorochrome-coupled lectins with different sugar specificities were applied to cryosections of dogfish kidney. Despite profound differences in renal architecture between elasmobranch fish and other vertebrates, the sequence of nephron segments as revealed by the lectin-binding pattern was rather similar to that of tetrapodes. Wheat germ agglutinin (WGA) bound to cell membranes of epithelial cells of glomeruli, proximal and distal tubules, their basement membranes, the collecting tubule, and epithelial cells. Among other broadly binding lectins were Ricinus communis agglutinin I (RCA-I), soybean agglutinin (SBA), peanut agglutinin (PNA), Lycopersicon esculentum agglutinin (LEA), and Jacalin, all of which marked proximal as well as distal portions of the renal tubule. Dolichos biflorus agglutinin (DBA) did not react with any renal structure. Ulex europaeus agglutinin I (UEA-I), which indicates the presence of alpha-L-fucose, very strongly and specifically marked single epithelial cells of the early distal nephron, all epithelial cells of the late distal tubule, the beginning of the collecting tubule in the mesial tissue zone, and single cells in the end portion of the collecting tubule in the lateral bundles. Binding of UEA-I to receptors of distal nephron cells could be useful for the identification of these cells in functional studies employing teased tubule and/or isolated cell preparations. Binding of UEA-I to dogfish kidney structures resembles staining with UEA-I conjugates of late distal tubules and collecting tubules in the kidneys of frog and other, higher vertebrates. Epithelial cells of early developmental stages showed, very rarely, binding sites for most lectin-fluorochrome conjugates. A large number of lectin binding sites was observed in the extracellular matrix of fibroblast layers surrounding the early anlage and the S-shaped body. Lectin binding sites of the nephron epithelia appeared in a sequential manner in the next stages of development of the nephron. Ontogenetic and phylogenetic aspects of the merging region between nephron proper (late distal tubule) and collecting system (collecting tubule) are discussed.

show abstract

Renal architecture of the dogfish Scyliorhinus caniculus (Chondrichthyes, Elasmobranchii)

Cited by 19 publications

References 19 publications

Renal blood vascular system in the elasmobranch, Raja erinacea mitchill, in relation to kidney zones

Renal blood vascular system in the elasmobranch, Raja erinacea mitchill, in relation to kidney zones

Developing nephrons in adolescent dogfish, Scyliorhinus caniculus (L.), with reference to ultrastructure of early stages, histogenesis of the renal countercurrent system, and nephron segmentation in marine elasmobranchs

Heterogenous distribution of glycoconjugates in the kidney of dogfish Scyliorhinus caniculus (l.) with reference to changes in the glycosylation pattern during ontogenetic development of the nephron

Contact Info

Product

Resources

About